STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE12398.1COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR001670; KEGG: pgn:PGN_0724 NAD-dependent 4-hydroxybutyrate dehydrogenase; PFAM: Alcohol dehydrogenase, iron-type; PRIAM: 4-hydroxybutyrate dehydrogenase; SPTR: Alcohol dehydrogenase, iron-dependent; IMG reference gene:2504824325; PFAM: Iron-containing alcohol dehydrogenase. (371 aa)    
Predicted Functional Partners:
AEE12397.1
Acetaldehyde dehydrogenase (acetylating); COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: pgn:PGN_0723 succinate-semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase; PRIAM: Acetaldehyde dehydrogenase (acetylating); SPTR: Aldehyde-alcohol dehydrogenase family protein; IMG reference gene:2504824324; PFAM: Aldehyde dehydrogenase family.
 0.999
AEE12399.1
COGs: COG0427 Acetyl-CoA hydrolase; InterPro IPR003702; KEGG: pgi:PG0690 4-hydroxybutyrate CoA-transferase; PFAM: Acetyl-CoA hydrolase/transferase; SPTR: 4-hydroxybutyrate coenzyme A transferase; IMG reference gene:2504824326; PFAM: Acetyl-CoA hydrolase/transferase N-terminal domain.
  
 
 0.976
AEE13278.1
COGs: COG0427 Acetyl-CoA hydrolase; InterPro IPR003702; KEGG: pgi:PG1956 4-hydroxybutyrate CoA-transferase; PFAM: Acetyl-CoA hydrolase/transferase; SPTR: 4-hydroxybutyrate coenzyme A transferase; IMG reference gene:2504825258; PFAM: Acetyl-CoA hydrolase/transferase N-terminal domain.
  
 
 0.911
AEE12402.1
Vinylacetyl-CoA Delta-isomerase; COGs: COG2368 Aromatic ring hydroxylase; InterPro IPR004925; KEGG: pgi:PG0692 4-hydroxybutyryl-CoA dehydratase; PFAM: 4-hydroxyphenylacetate 3-hydroxylase; PRIAM: Vinylacetyl-CoA Delta-isomerase; SPTR: Gamma-aminobutyrate metabolism dehydratase/isomerase; IMG reference gene:2504824329; PFAM: 4-hydroxyphenylacetate 3-hydroxylase N terminal; 4-hydroxyphenylacetate 3-hydroxylase C terminal.
 
   
 0.805
AEE12812.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: pgn:PGN_1418 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SPTR: Pyruvate synthase; TIGRFAM: Pyruvate-flavodoxin [...]
  
  
 0.723
AEE12465.1
Starch synthase; COGs: COG0297 Glycogen synthase; InterPro IPR013534; KEGG: pgn:PGN_1736 putative glycogen synthase; PFAM: Starch synthase catalytic region; PRIAM: Starch synthase; SPTR: Starch synthase catalytic domain protein; IMG reference gene:2504824394; PFAM: Starch synthase catalytic domain.
   
    0.679
AEE13279.1
Alcohol dehydrogenase (NADP(+)); COGs: COG1979 Uncharacterized oxidoreductase Fe-dependent alcohol dehydrogenase family; InterPro IPR001670; KEGG: bth:BT_0535 iron-containing alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, iron-type; PRIAM: Alcohol dehydrogenase (NADP(+)); SPTR: Putative alcohol dehydrogenase 3; IMG reference gene:2504825259; PFAM: Iron-containing alcohol dehydrogenase.
  
   
 0.633
AEE12401.1
Nitrogen-fixing NifU domain-containing protein; InterPro IPR001075; KEGG: pgn:PGN_0726 hypothetical protein; PFAM: NIF system FeS cluster assembly, NifU, C-terminal; SPTR: NifU-like protein; IMG reference gene:2504824328; PFAM: NifU-like domain.
 
     0.632
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
   
  
 0.523
AEE12072.1
KEGG: pgn:PGN_0458 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504823995.
   
    0.505
Your Current Organism:
Porphyromonas asaccharolytica
NCBI taxonomy Id: 879243
Other names: P. asaccharolytica DSM 20707, Porphyromonas asaccharolytica ATCC 25260, Porphyromonas asaccharolytica CCUG 7834, Porphyromonas asaccharolytica DSM 20707, Porphyromonas asaccharolytica JCM 6326, Porphyromonas asaccharolytica str. DSM 20707, Porphyromonas asaccharolytica strain DSM 20707
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