Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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AEE12970.1AMP nucleosidase; COGs: COG0775 Nucleoside phosphorylase; InterPro IPR010944:IPR000845; KEGG: pgn:PGN_1002 AMP nucleosidase; PFAM: Nucleoside phosphorylase; SPTR: Putative AMP nucleosidase; TIGRFAM: AMP nucleosidase, putative; IMG reference gene:2504824933; PFAM: Phosphorylase superfamily; TIGRFAM: AMP nucleosidase, putative. (258 aa)    
Predicted Functional Partners:
AEE12697.1
Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
 0.907
AEE13189.1
UDP-sugar diphosphatase; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334; KEGG: pru:PRU_1666 5'-nucleotidase family protein; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; PRIAM: UDP-sugar diphosphatase; SPTR: 5'-nucleotidase, C-terminal domain protein; IMG reference gene:2504825167; PFAM: 5'-nucleotidase, C-terminal domain; Calcineurin-like phosphoesterase; Belongs to the 5'-nucleotidase family.
     
 0.902
AEE13250.1
COGs: COG0015 Adenylosuccinate lyase; InterPro IPR004769:IPR000362:IPR013539; KEGG: pgi:PG1123 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase C-terminal; Fumarate lyase; PRIAM: Adenylosuccinate lyase; SPTR: Adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; IMG reference gene:2504825230; PFAM: Lyase; Adenylosuccinate lyase C-terminal; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
 
  0.901
surE
Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.900
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
  0.900
AEE12971.1
COGs: COG1466 DNA polymerase III delta subunit; InterPro IPR005790:IPR010372; KEGG: pgn:PGN_1001 hypothetical protein; PFAM: DNA polymerase III, delta; SPTR: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; IMG reference gene:2504824934; PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit.
       0.765
AEE12969.1
KEGG: pgn:PGN_1003 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504824932.
       0.559
AEE12968.1
COGs: COG4152 ABC-type uncharacterized transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: pgi:PG0946 ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Monosaccharide-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Putative phage tail component, N-terminal domain protein; IMG reference gene:2504824931; PFAM: ABC transporter.
       0.503
AEE12967.1
Putative ABC transporter permease protein; COGs: COG1668 ABC-type Na+ efflux pump permease component; KEGG: pgn:PGN_1005 probable ABC transporter permease protein; SPTR: Putative ABC transporter, permease protein; IMG reference gene:2504824930.
       0.496
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
   
 
 0.424
Your Current Organism:
Porphyromonas asaccharolytica
NCBI taxonomy Id: 879243
Other names: P. asaccharolytica DSM 20707, Porphyromonas asaccharolytica ATCC 25260, Porphyromonas asaccharolytica CCUG 7834, Porphyromonas asaccharolytica DSM 20707, Porphyromonas asaccharolytica JCM 6326, Porphyromonas asaccharolytica str. DSM 20707, Porphyromonas asaccharolytica strain DSM 20707
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