STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (327 aa)    
Predicted Functional Partners:
pgi
COGs: COG0166 Glucose-6-phosphate isomerase; HAMAP: Phosphoglucose isomerase (PGI); InterPro IPR001672; KEGG: pgn:PGN_1155 glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase (PGI); PRIAM: Glucose-6-phosphate isomerase; SPTR: Glucose-6-phosphate isomerase; IMG reference gene:2504825412; PFAM: Phosphoglucose isomerase; Belongs to the GPI family.
  
 0.982
fda
COGs: COG3588 Fructose-1 6-bisphosphate aldolase; HAMAP: Fructose-bisphosphate aldolase class 1; InterPro IPR000741; KEGG: pgn:PGN_1695 fructose-1,6-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase, class-I; SPTR: Fructose-bisphosphate aldolase class-I; IMG reference gene:2504825098; PFAM: Fructose-bisphosphate aldolase class-I.
  
 0.938
AEE12207.1
COGs: COG0021 Transketolase; InterPro IPR005474:IPR005475:IPR005476; KEGG: pgi:PG1748 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; PRIAM: Formaldehyde transketolase; SPTR: Transketolase, thiamine diphosphate binding domain protein; IMG reference gene:2504824131; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; Belongs to the transketolase family.
  
 
 0.933
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.930
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
   
  
 0.928
AEE12591.1
COGs: COG1482 Phosphomannose isomerase; InterPro IPR001250; KEGG: ppm:PPSC2_c1453 mannose-6-phosphate isomerase, class I; PFAM: Mannose-6-phosphate isomerase, type I; PRIAM: Mannose-6-phosphate isomerase; SPTR: Phosphomannose isomerase type I; IMG reference gene:2504824533; PFAM: Phosphomannose isomerase type I.
  
  
 0.923
fbp
Fructose-1,6-bisphosphatase class 3; COGs: COG3855 conserved hypothetical protein; HAMAP: Fructose-1,6-bisphosphatase, Bacillus type; InterPro IPR009164; KEGG: pgn:PGN_0816 fructose-1,6-bisphosphatase; PFAM: Fructose-1,6-bisphosphatase, Bacillus type; PRIAM: Fructose-bisphosphatase; SPTR: Firmicute fructose-1,6-bisphosphatase; IMG reference gene:2504825633; PFAM: Firmicute fructose-1,6-bisphosphatase.
     
 0.915
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
  
 0.883
AEE13075.1
A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
       0.809
AEE12541.1
COGs: COG0058 Glucan phosphorylase; InterPro IPR000811:IPR011834; KEGG: pdi:BDI_2005 glycosyltransferase family alpha-glucan phosphorylase; PFAM: Glycosyl transferase, family 35; PRIAM: Phosphorylase; SPTR: Alpha-glucan phosphorylase; TIGRFAM: Alpha-glucan phosphorylase; IMG reference gene:2504824473; PFAM: Carbohydrate phosphorylase; Protein of unknown function (DUF3417); TIGRFAM: alpha-glucan phosphorylases.
 
 
 0.773
Your Current Organism:
Porphyromonas asaccharolytica
NCBI taxonomy Id: 879243
Other names: P. asaccharolytica DSM 20707, Porphyromonas asaccharolytica ATCC 25260, Porphyromonas asaccharolytica CCUG 7834, Porphyromonas asaccharolytica DSM 20707, Porphyromonas asaccharolytica JCM 6326, Porphyromonas asaccharolytica str. DSM 20707, Porphyromonas asaccharolytica strain DSM 20707
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