STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
shn_19985Transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa)    
Predicted Functional Partners:
shn_19980
Calcium-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.797
shn_19995
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.792
shn_19990
DNA mismatch repair protein MutS; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.791
shn_19975
Membrane protein FxsA; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.544
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.489
shn_18485
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.463
secB
Protein-export chaperone SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
       0.441
shn_15385
Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.406
Your Current Organism:
Shinella sp. HZN7
NCBI taxonomy Id: 879274
Other names: S. sp. HZN7
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.