node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cmk | gmk | shn_01370 | shn_06350 | Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.735 |
cmk | pyrG | shn_01370 | shn_08485 | Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.789 |
cmk | pyrH | shn_01370 | shn_09370 | Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.855 |
cmk | shn_21310 | shn_01370 | shn_21310 | Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.634 |
dut | pyrH | shn_22320 | shn_09370 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.417 |
dut | shn_21310 | shn_22320 | shn_21310 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.653 |
gmk | cmk | shn_06350 | shn_01370 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.735 |
gmk | pyrG | shn_06350 | shn_08485 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.540 |
gmk | pyrH | shn_06350 | shn_09370 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.838 |
gmk | rpoA | shn_06350 | shn_07625 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.404 |
gmk | rpoB | shn_06350 | shn_07450 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.433 |
gmk | rpoC | shn_06350 | shn_07455 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.559 |
gmk | rpoZ | shn_06350 | shn_05945 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.934 |
gmk | shn_05950 | shn_06350 | shn_05950 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.937 |
gmk | shn_21310 | shn_06350 | shn_21310 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.639 |
pyrG | cmk | shn_08485 | shn_01370 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.789 |
pyrG | gmk | shn_08485 | shn_06350 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.540 |
pyrG | pyrH | shn_08485 | shn_09370 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.866 |
pyrG | rpoA | shn_08485 | shn_07625 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.658 |
pyrG | rpoB | shn_08485 | shn_07450 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.820 |