close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGS30343.1Conserved domain protein. (1603 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
    0.907
EGS30209.1
Hydrolase, alpha/beta domain protein.
  
     0.699
EGS31444.1
Hypothetical protein.
  
     0.672
EGS30757.1
Hypothetical protein.
 
     0.634
EGS30830.1
TrkA N-terminal domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.
 
     0.613
EGS29706.1
Hypothetical protein.
  
     0.582
EGS31645.1
Hypothetical protein.
 
    0.571
EGS30697.1
DnaJ domain protein.
  
     0.527
EGS30226.1
C-terminal domain protein of bacterial fibrinogen-binding adhesin; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.
  
 
 0.505
EGS31723.1
Hypothetical protein.
  
     0.500
Your Current Organism:
Peptoniphilus sp. F0436
NCBI taxonomy Id: 879308
Other names: P. sp. oral taxon 375 str. F0436, Peptoniphilus sp. oral taxon 375 str. F0436
Server load: low (32%) [HD]