| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFR60323.1 | EFR60418.1 | HMPREF9199_2017 | HMPREF9199_2016 | Membrane protein insertase, YidC/Oxa1 family; Identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592. | R3H domain protein; Identified by match to protein family HMM PF01424. | 0.949 |
| EFR60323.1 | gidA | HMPREF9199_2017 | HMPREF9199_2014 | Membrane protein insertase, YidC/Oxa1 family; Identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592. | tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.723 |
| EFR60323.1 | gidB | HMPREF9199_2017 | HMPREF9199_2011 | Membrane protein insertase, YidC/Oxa1 family; Identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592. | 16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | 0.592 |
| EFR60323.1 | guaB | HMPREF9199_2017 | HMPREF9199_1064 | Membrane protein insertase, YidC/Oxa1 family; Identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.498 |
| EFR60323.1 | trmE | HMPREF9199_2017 | HMPREF9199_2015 | Membrane protein insertase, YidC/Oxa1 family; Identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.671 |
| EFR60340.1 | gidB | HMPREF9199_2005 | HMPREF9199_2011 | Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family. | 16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | 0.745 |
| EFR60340.1 | soj | HMPREF9199_2005 | HMPREF9199_2006 | Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family. | Sporulation initiation inhibitor protein Soj; Identified by match to protein family HMM PF01656. | 0.997 |
| EFR60418.1 | EFR60323.1 | HMPREF9199_2016 | HMPREF9199_2017 | R3H domain protein; Identified by match to protein family HMM PF01424. | Membrane protein insertase, YidC/Oxa1 family; Identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592. | 0.949 |
| EFR60418.1 | gidA | HMPREF9199_2016 | HMPREF9199_2014 | R3H domain protein; Identified by match to protein family HMM PF01424. | tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.512 |
| EFR60418.1 | gidB | HMPREF9199_2016 | HMPREF9199_2011 | R3H domain protein; Identified by match to protein family HMM PF01424. | 16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | 0.778 |
| EFR60418.1 | trmE | HMPREF9199_2016 | HMPREF9199_2015 | R3H domain protein; Identified by match to protein family HMM PF01424. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.605 |
| EFR60968.1 | gidB | HMPREF9199_1253 | HMPREF9199_2011 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | 0.610 |
| EFR60968.1 | guaB | HMPREF9199_1253 | HMPREF9199_1064 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.770 |
| gidA | EFR60323.1 | HMPREF9199_2014 | HMPREF9199_2017 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | Membrane protein insertase, YidC/Oxa1 family; Identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592. | 0.723 |
| gidA | EFR60418.1 | HMPREF9199_2014 | HMPREF9199_2016 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | R3H domain protein; Identified by match to protein family HMM PF01424. | 0.512 |
| gidA | gidB | HMPREF9199_2014 | HMPREF9199_2011 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | 0.880 |
| gidA | guaB | HMPREF9199_2014 | HMPREF9199_1064 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.425 |
| gidA | trmE | HMPREF9199_2014 | HMPREF9199_2015 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.999 |
| gidB | EFR60323.1 | HMPREF9199_2011 | HMPREF9199_2017 | 16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | Membrane protein insertase, YidC/Oxa1 family; Identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592. | 0.592 |
| gidB | EFR60340.1 | HMPREF9199_2011 | HMPREF9199_2005 | 16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family. | 0.745 |