A0A0J0XB81 protein (Cutaneotrichosporon oleaginosum)

Nodes:

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second shell of interactors

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a 3D structure is known or predicted

Edges:

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

A0A0J0XB81

Pkinase-domain-containing protein. (413 aa)

Predicted Functional Partners:

A0A0J0XLJ3

0.883

A0A0J0XGQ6

0.601

A0A0J0XNE8

0.460

A0A0J1AUT5

0.454

A0A0J0XI68

0.415

A0A0J0XX68

0.410

Your Current Organism:

Cutaneotrichosporon oleaginosum

NCBI taxonomy Id: 879819
Other names: ATCC 20509, C. oleaginosum, Cutaneotrichosporon oleaginosum (J.J. Zhou, S.O. Suh & Gujjari) Xin Zhan Liu, F.Y. Bai, M. Groenew. & Boekhout, 2015, Trichosporon oleaginosum, Trichosporon oleaginosum J.J. Zhou, S.O. Suh & Gujjari, 2011, Trichosporon oleaginosus, Trichosporon sp. ATCC 20508, Trichosporon sp. ATCC 20509

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A0J0XB81	A0A0J0XGQ6	Pkinase-domain-containing protein.	Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family.	0.601
A0A0J0XB81	A0A0J0XI68	Pkinase-domain-containing protein.	Kinase-like protein; Belongs to the protein kinase superfamily.	0.415
A0A0J0XB81	A0A0J0XLJ3	Pkinase-domain-containing protein.	cAMP-dependent protein kinase regulatory subunit.	0.883
A0A0J0XB81	A0A0J0XNE8	Pkinase-domain-containing protein.	Non-specific serine/threonine protein kinase.	0.460
A0A0J0XB81	A0A0J0XX68	Pkinase-domain-containing protein.	Pkinase-domain-containing protein.	0.410
A0A0J0XB81	A0A0J1AUT5	Pkinase-domain-containing protein.	Non-specific serine/threonine protein kinase.	0.454
A0A0J0XGQ6	A0A0J0XB81	Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family.	Pkinase-domain-containing protein.	0.601
A0A0J0XI68	A0A0J0XB81	Kinase-like protein; Belongs to the protein kinase superfamily.	Pkinase-domain-containing protein.	0.415
A0A0J0XLJ3	A0A0J0XB81	cAMP-dependent protein kinase regulatory subunit.	Pkinase-domain-containing protein.	0.883
A0A0J0XLJ3	A0A0J0XNE8	cAMP-dependent protein kinase regulatory subunit.	Non-specific serine/threonine protein kinase.	0.558
A0A0J0XLJ3	A0A0J1AUT5	cAMP-dependent protein kinase regulatory subunit.	Non-specific serine/threonine protein kinase.	0.917
A0A0J0XNE8	A0A0J0XB81	Non-specific serine/threonine protein kinase.	Pkinase-domain-containing protein.	0.460
A0A0J0XNE8	A0A0J0XLJ3	Non-specific serine/threonine protein kinase.	cAMP-dependent protein kinase regulatory subunit.	0.558
A0A0J0XNE8	A0A0J0XX68	Non-specific serine/threonine protein kinase.	Pkinase-domain-containing protein.	0.906
A0A0J0XX68	A0A0J0XB81	Pkinase-domain-containing protein.	Pkinase-domain-containing protein.	0.410
A0A0J0XX68	A0A0J0XNE8	Pkinase-domain-containing protein.	Non-specific serine/threonine protein kinase.	0.906
A0A0J0XX68	A0A0J1AUT5	Pkinase-domain-containing protein.	Non-specific serine/threonine protein kinase.	0.905
A0A0J1AUT5	A0A0J0XB81	Non-specific serine/threonine protein kinase.	Pkinase-domain-containing protein.	0.454
A0A0J1AUT5	A0A0J0XLJ3	Non-specific serine/threonine protein kinase.	cAMP-dependent protein kinase regulatory subunit.	0.917
A0A0J1AUT5	A0A0J0XX68	Non-specific serine/threonine protein kinase.	Pkinase-domain-containing protein.	0.905

Network Stats

number of nodes:

2

number of edges:

1

average node degree:

1

avg. local clustering coefficient:

1

expected number of edges:

1

PPI enrichment p-value:

0.5

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000724

Double-strand break repair via homologous recombination

3 of 4

2.43

1.93

0.00054

GO:0006281

DNA repair

4 of 50

1.46

1.23

0.0020

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003690

Double-stranded DNA binding

3 of 14

1.89

1.25

0.0057

GO:0003678

DNA helicase activity

3 of 14

1.89

1.25

0.0057

GO:0004527

Exonuclease activity

3 of 20

1.73

1.2

0.0057

GO:0016887

ATP hydrolysis activity

3 of 41

1.42

0.86

0.0179

GO:0008408

3-5 exonuclease activity

2 of 9

1.9

0.86

0.0319

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0033202

DNA helicase complex

3 of 8

2.13

2.0

0.00027

GO:1902494

Catalytic complex

4 of 68

1.33

1.21

0.00092

GO:0032991

Protein-containing complex

5 of 170

1.03

0.88

0.0011

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1230

PD-(D/E)XK nuclease superfamily, and CBS domain

4 of 6

2.38

3.11

3.40e-06

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0033202

DNA helicase complex

3 of 13

1.92

1.48

0.0020

GOCC:0044815

DNA packaging complex

3 of 15

1.86

1.46

0.0020

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0269

Exonuclease

3 of 11

1.99

1.9

0.00033

KW-0234

DNA repair

4 of 31

1.67

1.72

0.00024

KW-0227

DNA damage

4 of 31

1.67

1.72

0.00024

KW-0347

Helicase

3 of 20

1.73

1.5

0.0012

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13361

UvrD-like helicase C-terminal domain

3 of 3

2.56

2.31

0.00013

PF12705

PD-(D/E)XK nuclease superfamily

3 of 4

2.43

2.28

0.00013

PF13245

AAA domain

2 of 5

2.16

0.99

0.0212

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR038726

PD-(D/E)XK endonuclease-like domain, AddAB-type

3 of 4

2.43

1.92

0.00058

IPR011604

PD-(D/E)XK endonuclease-like domain superfamily

3 of 4

2.43

1.92

0.00058

IPR011335

Restriction endonuclease type II-like

3 of 7

2.19

1.82

0.00067

IPR014016

UvrD-like helicase, ATP-binding domain

3 of 8

2.13

1.8

0.00068

IPR000212

DNA helicase, UvrD/REP type

3 of 8

2.13

1.8

0.00068

(more ...)

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