A0A0J0XLA2 protein (Cutaneotrichosporon oleaginosum)

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second shell of interactors

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a 3D structure is known or predicted

Edges:

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

A0A0J0XLA2

Uncharacterized protein. (113 aa)

Predicted Functional Partners:

A0A0J0XB48

0.981

A0A0J0XYQ8

0.981

A0A0J0XW36

0.660

A0A0J1ATX3

0.660

A0A0J1AY52

0.660

A0A0J0XH02

0.645

A0A0J0XBS3

0.579

A0A0J0XC21

0.579

A0A0J0XHA6

0.579

A0A0J0XE61

0.571

Your Current Organism:

Cutaneotrichosporon oleaginosum

NCBI taxonomy Id: 879819
Other names: ATCC 20509, C. oleaginosum, Cutaneotrichosporon oleaginosum (J.J. Zhou, S.O. Suh & Gujjari) Xin Zhan Liu, F.Y. Bai, M. Groenew. & Boekhout, 2015, Trichosporon oleaginosum, Trichosporon oleaginosum J.J. Zhou, S.O. Suh & Gujjari, 2011, Trichosporon oleaginosus, Trichosporon sp. ATCC 20508, Trichosporon sp. ATCC 20509

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A0J0XB48	A0A0J0XBS3	HSF_DOMAIN domain-containing protein.	Heat-shock protein 90.	0.884
A0A0J0XB48	A0A0J0XC21	HSF_DOMAIN domain-containing protein.	Uncharacterized protein.	0.884
A0A0J0XB48	A0A0J0XE61	HSF_DOMAIN domain-containing protein.	Cyanovirin-N.	0.815
A0A0J0XB48	A0A0J0XH02	HSF_DOMAIN domain-containing protein.	Putative heat shock protein.	0.817
A0A0J0XB48	A0A0J0XHA6	HSF_DOMAIN domain-containing protein.	Flavin_Reduct domain-containing protein.	0.884
A0A0J0XB48	A0A0J0XLA2	HSF_DOMAIN domain-containing protein.	Uncharacterized protein.	0.981
A0A0J0XB48	A0A0J0XW36	HSF_DOMAIN domain-containing protein.	HSF_DOMAIN domain-containing protein.	0.513
A0A0J0XB48	A0A0J0XYQ8	HSF_DOMAIN domain-containing protein.	Response regulatory domain-containing protein.	0.808
A0A0J0XB48	A0A0J1ATX3	HSF_DOMAIN domain-containing protein.	HSF_DOMAIN domain-containing protein.	0.525
A0A0J0XB48	A0A0J1AY52	HSF_DOMAIN domain-containing protein.	Winged helix DNA-binding domain-containing protein.	0.465
A0A0J0XBS3	A0A0J0XB48	Heat-shock protein 90.	HSF_DOMAIN domain-containing protein.	0.884
A0A0J0XBS3	A0A0J0XE61	Heat-shock protein 90.	Cyanovirin-N.	0.872
A0A0J0XBS3	A0A0J0XH02	Heat-shock protein 90.	Putative heat shock protein.	0.891
A0A0J0XBS3	A0A0J0XLA2	Heat-shock protein 90.	Uncharacterized protein.	0.579
A0A0J0XBS3	A0A0J0XW36	Heat-shock protein 90.	HSF_DOMAIN domain-containing protein.	0.875
A0A0J0XBS3	A0A0J0XYQ8	Heat-shock protein 90.	Response regulatory domain-containing protein.	0.884
A0A0J0XBS3	A0A0J1ATX3	Heat-shock protein 90.	HSF_DOMAIN domain-containing protein.	0.726
A0A0J0XBS3	A0A0J1AY52	Heat-shock protein 90.	Winged helix DNA-binding domain-containing protein.	0.726
A0A0J0XC21	A0A0J0XB48	Uncharacterized protein.	HSF_DOMAIN domain-containing protein.	0.884
A0A0J0XC21	A0A0J0XE61	Uncharacterized protein.	Cyanovirin-N.	0.872

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

14

PPI enrichment p-value:

1.11e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003700

DNA-binding transcription factor activity

5 of 81

1.2

0.94

0.0035

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2296

UbiC transcription regulator-associated

3 of 5

2.19

1.65

0.0011

CL:1696

Duplicated hybrid motif, and Glucose permease domain IIB

3 of 12

1.81

1.29

0.0034

CL:1699

Glucose permease domain IIB

2 of 6

1.94

0.89

0.0256

CL:1685

Import into cell, and Hydrolase activity, hydrolyzing O-glycosyl compounds

4 of 120

0.94

0.53

0.0377

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0598

Phosphotransferase system

3 of 27

1.46

1.02

0.0066

KW-0805

Transcription regulation

5 of 96

1.13

0.91

0.0026

KW-0762

Sugar transport

3 of 35

1.35

0.89

0.0107

KW-0238

DNA-binding

5 of 146

0.95

0.69

0.0061

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00367

Phosphotransferase system, EIIB

3 of 12

1.81

1.18

0.0059

PF02378

Phosphotransferase system, EIIC

3 of 24

1.51

0.86

0.0186

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR028978

Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily

4 of 11

1.98

2.01

0.00013

IPR011663

UbiC transcription regulator-associated

4 of 11

1.98

2.01

0.00013

IPR000524

Transcription regulator HTH, GntR

4 of 14

1.87

1.94

0.00013

IPR036878

Glucose permease domain IIB

3 of 12

1.81

1.25

0.0042

IPR018113

Phosphotransferase system EIIB, cysteine phosphorylation site

3 of 12

1.81

1.25

0.0042

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00866

The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain that has a similar fold to PUBMED:12757941. It is believed to modulate activity of bacterial transcription factors in response to binding small molecules.

4 of 11

1.98

2.46

1.19e-05

SM00345

Helix_turn_helix gluconate operon transcriptional repressor

4 of 14

1.87

2.34

1.33e-05

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