STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A0J1AZ83Uncharacterized protein. (403 aa)    
Predicted Functional Partners:
A0A0J0XI58
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 0.998
A0A0J1AY31
DNA helicase; Belongs to the MCM family.
   
  
 0.894
A0A0J0XEJ1
DNA helicase; Belongs to the MCM family.
   
  
 0.888
A0A0J0XGY9
DNA helicase; Belongs to the MCM family.
   
  
 0.880
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
  
 0.878
A0A0J0XPD3
Cryptococcus neoformans thymidylate synthase complexed with substrate and an Antifolate.
   
  
 0.874
A0A0J0XPL4
DNA helicase; Belongs to the MCM family.
   
  
 0.865
A0A0J0XQ18
DNA helicase; Belongs to the MCM family.
   
  
 0.856
A0A0J0XXK2
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 
 0.856
A0A0J1B9G8
Thymidylate kinase.
   
 
 0.816
Your Current Organism:
Cutaneotrichosporon oleaginosum
NCBI taxonomy Id: 879819
Other names: ATCC 20509, C. oleaginosum, Cutaneotrichosporon oleaginosum (J.J. Zhou, S.O. Suh & Gujjari) Xin Zhan Liu, F.Y. Bai, M. Groenew. & Boekhout, 2015, Trichosporon oleaginosum, Trichosporon oleaginosum J.J. Zhou, S.O. Suh & Gujjari, 2011, Trichosporon oleaginosus, Trichosporon sp. ATCC 20508, Trichosporon sp. ATCC 20509
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