STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEL25487.1Manganese/iron superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (201 aa)    
Predicted Functional Partners:
AEL28240.1
Pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: domain; Domain of unknown function; 4Fe-4S binding domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; [...]
  
  
 0.845
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
 
 0.731
rplQ
PFAM: Ribosomal protein L17; TIGRFAM: ribosomal protein L17; COGs: COG0203 Ribosomal protein L17; HAMAP: 50S ribosomal protein L17; InterPro IPR000456; KEGG: mtt:Ftrac_3059 LSU ribosomal protein l17p; PFAM: Ribosomal protein L17; SPTR: 50S ribosomal protein L17; TIGRFAM: Ribosomal protein L17.
   
   0.729
rplM
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 
 0.725
rplO
Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
   
 
 0.718
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.715
rpsQ
30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
  
 
 0.711
ybeY
Metalloprotease ybeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
   
 
 0.707
AEL24118.1
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
   
 
 0.669
rplK
Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
   
   0.669
Your Current Organism:
Cyclobacterium marinum
NCBI taxonomy Id: 880070
Other names: C. marinum DSM 745, Cyclobacterium marinum DSM 745, Cyclobacterium marinum LMG 13164, Cyclobacterium marinum str. DSM 745, Cyclobacterium marinum strain DSM 745
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