STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adeAdenine deaminase; PFAM: Amidohydrolase family; TIGRFAM: adenine deaminase; COGs: COG1001 Adenine deaminase; HAMAP: Adenine deaminase; InterPro IPR006680:IPR006679; KEGG: fps:FP1059 adenine deaminase; PFAM: Amidohydrolase 1; SPTR: Adenine deaminase; TIGRFAM: Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. (544 aa)    
Predicted Functional Partners:
AEL24843.1
PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR005904:IPR000836; KEGG: bvu:BVU_1681 putative hypoxanthine guanine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; SPTR: Putative uncharacterized protein; TIGRFAM: Hypoxanthine phosphoribosyl transferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
  
 0.922
AEL26926.1
PFAM: Inosine-uridine preferring nucleoside hydrolase; COGs: COG1957 Inosine-uridine nucleoside N-ribohydrolase; InterPro IPR001910; KEGG: bpb:bpr_I0724 inosine-uridine preferring nucleoside hydrolase; PFAM: Inosine/uridine-preferring nucleoside hydrolase; SPTR: Inosine-uridine preferring nucleoside hydrolase.
    
  0.903
AEL26464.1
Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
 0.902
AEL25748.1
Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: dfe:Dfer_0345 histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SPTR: Histidine kinase.
       0.636
cmk
PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase; COGs: COG0283 Cytidylate kinase; HAMAP: Cytidylate kinase; InterPro IPR000623:IPR011994:IPR003136; KEGG: dfe:Dfer_5748 cytidylate kinase; PFAM: Cytidylate kinase region; Shikimate kinase; SPTR: Cytidylate kinase; TIGRFAM: Cytidylate kinase.
       0.551
ispH-2
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
       0.521
Your Current Organism:
Cyclobacterium marinum
NCBI taxonomy Id: 880070
Other names: C. marinum DSM 745, Cyclobacterium marinum DSM 745, Cyclobacterium marinum LMG 13164, Cyclobacterium marinum str. DSM 745, Cyclobacterium marinum strain DSM 745
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