STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFM02617.1PFAM: Adenylate and Guanylate cyclase catalytic domain; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (562 aa)    
Predicted Functional Partners:
AFM02616.1
PFAM: Adenylate and Guanylate cyclase catalytic domain; Tetratricopeptide repeat; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
 
  
 
0.962
AFM04475.1
PFAM: Nucleoside diphosphate kinase; Belongs to the NDK family.
    
 0.905
AFM05953.1
PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.904
AFM04050.1
(p)ppGpp synthetase, RelA/SpoT family; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
  0.900
AFM06331.1
Hypothetical protein; PFAM: CYTH domain.
     
  0.900
AFM06383.1
Putative ATPase; PFAM: Protein kinase domain; GAF domain; Stage II sporulation protein E (SpoIIE).
  
 0.886
folE
PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I.
     
  0.800
folE-2
PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I.
     
  0.800
ribBA
GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
  0.800
AFM02618.1
Metal-dependent hydrolase, beta-lactamase superfamily III; PFAM: Metallo-beta-lactamase superfamily; Cyclic nucleotide-binding domain.
 
 0.735
Your Current Organism:
Bernardetia litoralis
NCBI taxonomy Id: 880071
Other names: B. litoralis DSM 6794, Bernardetia litoralis DSM 6794, Flexibacter litoralis ATCC 23117, Flexibacter litoralis DSM 6794, Flexibacter litoralis IFO 15988
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.