node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEB08371.1 | AEB08373.1 | Desac_0485 | Desac_0487 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: sfu:Sfum_1747 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504154012. | 0.411 |
AEB08371.1 | gyrB | Desac_0485 | Desac_0486 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.904 |
AEB08373.1 | AEB08371.1 | Desac_0487 | Desac_0485 | KEGG: sfu:Sfum_1747 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504154012. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.411 |
AEB08373.1 | AEB08374.1 | Desac_0487 | Desac_0488 | KEGG: sfu:Sfum_1747 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504154012. | KEGG: dat:HRM2_33650 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504154013. | 0.524 |
AEB08373.1 | gyrB | Desac_0487 | Desac_0486 | KEGG: sfu:Sfum_1747 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504154012. | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.605 |
AEB08374.1 | AEB08373.1 | Desac_0488 | Desac_0487 | KEGG: dat:HRM2_33650 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504154013. | KEGG: sfu:Sfum_1747 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504154012. | 0.524 |
AEB08374.1 | gyrB | Desac_0488 | Desac_0486 | KEGG: dat:HRM2_33650 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504154013. | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.422 |
gyrB | AEB08371.1 | Desac_0486 | Desac_0485 | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.904 |
gyrB | AEB08373.1 | Desac_0486 | Desac_0487 | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | KEGG: sfu:Sfum_1747 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504154012. | 0.605 |
gyrB | AEB08374.1 | Desac_0486 | Desac_0488 | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | KEGG: dat:HRM2_33650 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504154013. | 0.422 |