STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (280 aa)    
Predicted Functional Partners:
AEB10128.1
COGs: COG0095 Lipoate-protein ligase A; InterPro IPR004143; KEGG: sth:STH1918 putative lipoate protein ligase; PFAM: Biotin/lipoate A/B protein ligase; SPTR: Putative lipoate protein ligase; manually curated; IMG reference gene:2504155862; PFAM: Biotin/lipoate A/B protein ligase family.
 
 
 0.951
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.904
AEB08857.1
COGs: COG0509 Glycine cleavage system H protein (lipoate-binding); InterPro IPR002930; KEGG: sfu:Sfum_2805 glycine cleavage H-protein; PFAM: Glycine cleavage H-protein; SPTR: Glycine cleavage H-protein; IMG reference gene:2504154523; PFAM: Glycine cleavage H-protein.
 
 
 0.843
AEB10689.1
Dihydrolipoyllysine-residue acetyltransferase; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR000089:IPR004167:IPR001078; KEGG: gme:Gmet_2511 branched-chain alpha-keto acid dehydrogenase subunit E2; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Biotin/lipoyl attachment; E3 binding; PRIAM: Dihydrolipoyllysine-residue acetyltransferase; SPTR: Pyruvate dehydrogenase complex E2 component, dihydrolipoamide acetyltransferase; IMG reference gene:2504156461; PFAM: 2-oxoacid dehydrogenases acyltransferase [...]
 
  
 0.574
AEB08494.1
Cell division protein FtsK/SpoIIIE; COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR003593:IPR018541:IPR002543; KEGG: gur:Gura_4392 cell divisionFtsK/SpoIIIE; PFAM: Cell divisionFtsK/SpoIIIE; DNA translocase FtsK gamma; SMART: DNA translocase FtsK gamma; ATPase, AAA+ type, core; SPTR: FtsK/SpoIIIE family protein; IMG reference gene:2504154135; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family.
       0.472
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.454
AEB09132.1
Transketolase; COGs: COG0021 Transketolase; InterPro IPR005475:IPR005478:IPR005474:IPR005476; KEGG: pna:Pnap_4499 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; PRIAM: Formaldehyde transketolase; SMART: Transketolase-like, pyrimidine-binding domain; SPTR: Transketolase; TIGRFAM: Transketolase, bacterial-like; IMG reference gene:2504154810; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: transketolase, bacterial and yea [...]
   
    0.424
ubiE
Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).
    
 0.402
Your Current Organism:
Desulfobacca acetoxidans
NCBI taxonomy Id: 880072
Other names: D. acetoxidans DSM 11109, Desulfobacca acetoxidans DSM 11109, Desulfobacca acetoxidans str. DSM 11109, Desulfobacca acetoxidans strain DSM 11109
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