STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtnAMethylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (350 aa)    
Predicted Functional Partners:
AEB09265.1
COGs: COG0005 Purine nucleoside phosphorylase; InterPro IPR000845; KEGG: mfv:Mfer_0491 methylthioadenosine phosphorylase; PFAM: Nucleoside phosphorylase domain; PRIAM: S-methyl-5'-thioadenosine phosphorylase; SPTR: Similar to 5'-methylthioadenosine phosphorylase; IMG reference gene:2504154948; PFAM: Phosphorylase superfamily.
 
 
 0.966
AEB08389.1
L-fuculose-phosphate aldolase; COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: dbr:Deba_2710 class II aldolase/adducin family protein; PFAM: Class II aldolase/adducin, N-terminal; PRIAM: L-fuculose-phosphate aldolase; SPTR: Class II aldolase/adducin family protein; IMG reference gene:2504154028; PFAM: Class II Aldolase and Adducin N-terminal domain; TIGRFAM: L-ribulose-5-phosphate 4-epimerase.
 
  
 0.774
AEB08584.1
ErfK/YbiS/YcfS/YnhG family protein; COGs: COG1376 conserved hypothetical protein; InterPro IPR002482:IPR018392:IPR005490; KEGG: sfu:Sfum_0476 ErfK/YbiS/YcfS/YnhG family protein; PFAM: YkuD domain; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: ErfK/YbiS/YcfS/YnhG family protein; IMG reference gene:2504154233; PFAM: L,D-transpeptidase catalytic domain.
       0.741
AEB10703.1
COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: gsu:GSU3374 ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Ribulose-phosphate 3-epimerase; TIGRFAM: Ribulose-phosphate 3-epimerase; IMG reference gene:2504156475; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase.
  
   0.650
AEB08582.1
COGs: COG1751 conserved hypothetical protein; KEGG: tjr:TherJR_1556 protein of unknown function DUF1867; SPTR: Putative uncharacterized protein; IMG reference gene:2504154231; PFAM: Pyruvate kinase, alpha/beta domain.
       0.601
AEB08532.1
COGs: COG0077 Prephenate dehydratase; InterPro IPR002701:IPR020822:IPR001086:IPR002912; KEGG: glo:Glov_2150 chorismate mutase; PFAM: Prephenate dehydratase; Chorismate mutase, type II; Amino acid-binding ACT; SMART: Chorismate mutase; SPTR: Chorismate mutase; IMG reference gene:2504154179; PFAM: Prephenate dehydratase; ACT domain; Chorismate mutase type II.
     
 0.471
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
    0.465
pheS
COGs: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; HAMAP: Phenylalanyl-tRNA synthetase alpha chain 1, bacterial; InterPro IPR004188:IPR002319:IPR004529:IPR022911; KEGG: dps:DP1424 phenylalanyl-tRNA synthetase, alpha chain; PFAM: Phenylalanyl-tRNA synthetase; Phenylalanyl-tRNA synthetase, class II, N-terminal; SPTR: Phenylalanyl-tRNA synthetase alpha chain; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, alpha subunit; IMG reference gene:2504155863; PFAM: tRNA synthetases class II core domain (F); Aminoacyl tRNA synthetase class II, N-terminal domain; TIGRFAM: phenylalanyl-tRNA [...]
 
    0.463
speE
Spermine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
 
  
 0.452
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...]
  
    0.432
Your Current Organism:
Desulfobacca acetoxidans
NCBI taxonomy Id: 880072
Other names: D. acetoxidans DSM 11109, Desulfobacca acetoxidans DSM 11109, Desulfobacca acetoxidans str. DSM 11109, Desulfobacca acetoxidans strain DSM 11109
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