STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AEB08741.1Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: dat:HRM2_14290 two component transcriptional regulator (LuxR family protein); PFAM: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SMART: Transcription regulator LuxR, C-terminal; Signal transduction response regulator, receiver domain; SPTR: Two component transcriptional regulator (LuxR family protein); IMG reference gene:2504154396; PFAM: Resp [...] (222 aa)    
Predicted Functional Partners:
AEB08742.1
COGs: COG4585 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003594:IPR013656:IPR 013655:IPR013767:IPR011712; KEGG: nde:NIDE0578 hypothetical protein; PFAM: ATPase-like, ATP-binding domain; PAS fold-3; PAS fold-4; PAS fold; Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; PAS; PAC motif; SPTR: Putative uncharacterized protein; TIGRFAM: PAS; IMG reference gene:2504154397; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box.
 
 0.994
AEB07994.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003018:IPR003661:IPR 003594:IPR001789:IPR008207:IPR013655:IPR013767; KEGG: ava:Ava_1029 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-3; PAS fold; GAF; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/ph [...]
 
 
 0.974
AEB08403.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR001789:IPR003661:IPR003594:IPR000014:IPR 013656; KEGG: dal:Dalk_1072 multi-sensor hybrid histidine kinase; PFAM: Signal transduction response regulator, receiver domain; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain; SMART: Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain [...]
  
 
0.939
AEB10232.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003018:IPR003661:IPR003594; KEGG: dbr:Deba_2636 GAF sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; SPTR: GAF sensor signal transduction histidine kinase; IMG reference gene:2504155970; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kin [...]
 
 
 0.896
AEB08314.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR003018:IPR000014:IPR003661:IPR003594:IPR 001789:IPR013767; KEGG: sfu:Sfum_2401 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; GAF; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; GAF; PAS; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SPTR: Multi-sensor h [...]
  
 
 0.844
AEB08378.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR001610:IPR003018:IPR003661:IPR 003594:IPR001789:IPR013656:IPR013655; KEGG: sfu:Sfum_3112 putative PAS/PAC sensor protein; PFAM: ATPase-like, ATP-binding domain; PAS fold-3; GAF; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; GAF; PAS; PAC motif; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor [...]
  
 
 0.844
AEB09782.1
Putative PAS/PAC sensor protein; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR000014:IPR003018:IPR013767:IPR003594:IPR 001789; KEGG: dal:Dalk_5108 PAS/PAC sensor hybrid histidine kinase; PFAM: Signal transduction response regulator, receiver domain; GAF; PAS fold; ATPase-like, ATP-binding domain; SMART: Signal transduction response regulator, receiver domain; GAF; PAS; SPTR: ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; TIGRFAM: PAS; IMG reference gene:2504155500; PFAM: Response regulator receiver domain [...]
  
 
 0.844
AEB10746.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG3287 conserved hypothetical protein; InterProIPR013702:IPR019494:IPR013655:IPR013656:IPR 003594:IPR001789:IPR000014:IPR001610; KEGG: ppd:Ppro_2089 PAS/PAC sensor hybrid histidine kinase; PFAM: FIST domain, N-terminal; FIST C domain; PAS fold-3; PAS fold-4; ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; SMART: FIST domain, N-terminal; PAS; PAC motif; ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; SPTR: PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS [...]
  
 
 0.828
AEB08635.1
Multi-sensor signal transduction multi-kinase; COGs: COG0591 Na+/proline symporter; InterProIPR003018:IPR000014:IPR001610:IPR003661:IPR 003594:IPR001734:IPR013767; KEGG: geo:Geob_2606 protein serine phosphatase with GAF(s) sensor(s); PFAM: ATPase-like, ATP-binding domain; GAF; Sodium/solute symporter; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; GAF; PAS; PAC motif; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Putative phytochrome sensor protein; T [...]
  
 
 0.819
AEB08477.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR000014:IPR003594:IPR001789:IPR013656; KEGG: gsu:GSU1529 sensory box histidine kinase/response regulator; PFAM: ATPase-like, ATP-binding domain; PAS fold-4; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; PAS; Signal transduction response regulator, receiver domain; SPTR: Sensory box histidine kinase/response regulator; TIGRFAM: PAS; IMG reference gene:2504154118; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; PAS fold; TIGR [...]
  
 
 0.814
Your Current Organism:
Desulfobacca acetoxidans
NCBI taxonomy Id: 880072
Other names: D. acetoxidans DSM 11109, Desulfobacca acetoxidans DSM 11109, Desulfobacca acetoxidans str. DSM 11109, Desulfobacca acetoxidans strain DSM 11109
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