STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB08781.1N-6 DNA methylase; COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR003356; KEGG: mtp:Mthe_1211 N-6 DNA methylase; PFAM: DNA methylase, adenine-specific; SPTR: N-6 DNA methylase; IMG reference gene:2504154442; PFAM: N-6 DNA Methylase; HsdM N-terminal domain; TIGRFAM: type I restriction system adenine methylase (hsdM). (522 aa)    
Predicted Functional Partners:
AEB07973.1
Protein of unknown function DUF318, transmembrane; COGs: COG0610 Type I site-specific restriction-modification system R (restriction) subunit and related helicase; InterPro IPR007409:IPR005524; KEGG: dbr:Deba_2537 type I site-specific deoxyribonuclease, HsdR family; PFAM: Protein of unknown function DUF318, transmembrane; Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; SPTR: Type I site-specific deoxyribonuclease, HsdR family; IMG reference gene:2504153593; PFAM: Type I restriction enzyme R protein N terminus (HSDR_N); Predicted permease.
 
 
 0.975
AEB07974.1
Site-specific DNA-methyltransferase (adenine-specific); COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR003356:IPR000055; KEGG: pca:Pcar_2925 type I restriction-modification system methyltransferase subunit; PFAM: DNA methylase, adenine-specific; Restriction endonuclease, type I, S subunit, EcoBI; PRIAM: Site-specific DNA-methyltransferase (adenine-specific); SPTR: Type I restriction-modification system methyltransferase subunit; IMG reference gene:2504153594; PFAM: N-6 DNA Methylase; Type I restriction modification DNA specificity domain; Hs [...]
 
 
0.900
AEB08780.1
Filamentation induced by cAMP protein Fic; COGs: COG3177 conserved hypothetical protein; InterPro IPR003812; KEGG: syp:SYNPCC7002_F0100 Fic family protein; PFAM: Filamentation induced by cAMP/death on curing-related; SPTR: Fic family protein; IMG reference gene:2504154441; PFAM: Fic/DOC family.
  
   0.580
AEB08308.1
COGs: COG2865 transcriptional regulator protein; InterPro IPR007421; KEGG: dak:DaAHT2_2164 putative transcriptional regulator; PFAM: ATPase, AAA-4; SPTR: Putative transcriptional regulator; IMG reference gene:2504153945; PFAM: Divergent AAA domain.
  
    0.529
uvrB
UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...]
    
 
 0.440
AEB08782.1
Hypothetical protein; KEGG: ote:Oter_3111 nucleotide-binding protein; SPTR: Nucleotide-binding protein containing TIR-like protein domain-like protein; IMG reference gene:2504154443.
       0.425
Your Current Organism:
Desulfobacca acetoxidans
NCBI taxonomy Id: 880072
Other names: D. acetoxidans DSM 11109, Desulfobacca acetoxidans DSM 11109, Desulfobacca acetoxidans str. DSM 11109, Desulfobacca acetoxidans strain DSM 11109
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