STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AEB08797.1Phospho-2-dehydro-3-deoxyheptonate aldolase; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218:IPR006268; KEGG: sfu:Sfum_1777 3-deoxy-7-phosphoheptulonate synthase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: 3-deoxy-7-phosphoheptulonate synthase; TIGRFAM: Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2; IMG reference gene:2504154460; PFAM: DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase. (336 aa)    
Predicted Functional Partners:
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
 
 0.997
AEB08532.1
COGs: COG0077 Prephenate dehydratase; InterPro IPR002701:IPR020822:IPR001086:IPR002912; KEGG: glo:Glov_2150 chorismate mutase; PFAM: Prephenate dehydratase; Chorismate mutase, type II; Amino acid-binding ACT; SMART: Chorismate mutase; SPTR: Chorismate mutase; IMG reference gene:2504154179; PFAM: Prephenate dehydratase; ACT domain; Chorismate mutase type II.
 
  
 0.974
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
  
 0.706
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
  
 0.676
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
 
  
 0.599
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.576
AEB10502.1
Chorismate mutase; COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: sat:SYN_01933 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; PRIAM: Chorismate mutase; SPTR: Prephenate dehydrogenase; IMG reference gene:2504156249; PFAM: Prephenate dehydrogenase.
  
  
 0.472
AEB08796.1
Redoxin domain protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
       0.414
Your Current Organism:
Desulfobacca acetoxidans
NCBI taxonomy Id: 880072
Other names: D. acetoxidans DSM 11109, Desulfobacca acetoxidans DSM 11109, Desulfobacca acetoxidans str. DSM 11109, Desulfobacca acetoxidans strain DSM 11109
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