STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Experiments
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[Homology]
Score
AEB08859.1Two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR003593:IPR002078:IPR002197; KEGG: afw:Anae109_1798 two component, sigma54 specific, fis family transcriptional regulator; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver domain; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver domain; ATPase, AAA+ type, core; SPTR: Acetoacetate metabolism regulatory protei [...] (449 aa)    
Predicted Functional Partners:
AEB08860.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR000014:IPR003661:IPR003594:IPR013656; KEGG: sfu:Sfum_0826 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-4; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS; SPTR: Putative uncharacterized protein; TIGRFAM: PAS; IMG reference gene:2504154526; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [...]
 
 
 
 0.861
AEB09927.1
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.721
AEB08858.1
Peptidase zinc-dependent; COGs: COG1913 Zn-dependent protease; InterPro IPR012962; KEGG: sfu:Sfum_2804 peptidase, zinc-dependent; PFAM: Peptidase M54, archaemetzincin; SPTR: Peptidase, zinc-dependent; IMG reference gene:2504154524; PFAM: Peptidase family M54.
       0.686
AEB07994.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003018:IPR003661:IPR 003594:IPR001789:IPR008207:IPR013655:IPR013767; KEGG: ava:Ava_1029 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-3; PAS fold; GAF; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/ph [...]
  
 
0.589
AEB08148.1
Cobyrinic acid ac-diamide synthase; COGs: COG0455 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: dbr:Deba_2321 cobyrinic acid ac-diamide synthase; PFAM: Cobyrinic acid a,c-diamide synthase; SPTR: Cobyrinic acid a,c-diamide synthase; IMG reference gene:2504153776; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
  
 
 0.544
AEB10682.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR003018:IPR013767:IPR003661:IPR003594:IPR 000014:IPR001610; KEGG: dbr:Deba_0269 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; GAF; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; GAF; PAS; PAC motif; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: PAS/PAC sensor signal transduction histidine kinase; TIGR [...]
 
 
 
 0.442
AEB10232.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003018:IPR003661:IPR003594; KEGG: dbr:Deba_2636 GAF sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; SPTR: GAF sensor signal transduction histidine kinase; IMG reference gene:2504155970; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kin [...]
 
 
 
 0.430
AEB10401.1
COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterProIPR013767:IPR003661:IPR003594:IPR001789:IPR 000014:IPR001610; KEGG: dal:Dalk_3513 PAS/PAC sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; PAS; PAC motif; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; [...]
  
 
 0.429
AEB08314.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR003018:IPR000014:IPR003661:IPR003594:IPR 001789:IPR013767; KEGG: sfu:Sfum_2401 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; GAF; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; GAF; PAS; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SPTR: Multi-sensor h [...]
  
 
 0.419
AEB08378.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR001610:IPR003018:IPR003661:IPR 003594:IPR001789:IPR013656:IPR013655; KEGG: sfu:Sfum_3112 putative PAS/PAC sensor protein; PFAM: ATPase-like, ATP-binding domain; PAS fold-3; GAF; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; GAF; PAS; PAC motif; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor [...]
  
 
 0.419
Your Current Organism:
Desulfobacca acetoxidans
NCBI taxonomy Id: 880072
Other names: D. acetoxidans DSM 11109, Desulfobacca acetoxidans DSM 11109, Desulfobacca acetoxidans str. DSM 11109, Desulfobacca acetoxidans strain DSM 11109
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