STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB09009.1ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG0474 Cation transport ATPase; InterProIPR004014:IPR008250:IPR005834:IPR006068:IPR 001757; KEGG: rca:Rcas_0372 HAD superfamily ATPase; PFAM: ATPase, P-type, ATPase-associated domain; ATPase, P-type cation-transporter, N-terminal; Haloacid dehalogenase-like hydrolase; ATPase, P-type cation-transporter, C-terminal; PRIAM: Calcium-transporting ATPase; SMART: ATPase, P-type cation-transporter, N-terminal; SPTR: ATPase, P-type (Transporting), HAD superfamily, subfamily IC; TIGRFAM: ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H [...] (912 aa)    
Predicted Functional Partners:
AEB09010.1
COGs: COG1189 rRNA methylase; InterPro IPR002942:IPR002877:IPR004538; KEGG: gbm:Gbem_2654 rRNA methyltransferase, YqxC-like; PFAM: Ribosomal RNA methyltransferase RrmJ/FtsJ; RNA-binding S4; SMART: RNA-binding S4; SPTR: rRNA methyltransferase, YqxC-related, putative; TIGRFAM: Haemolysin A; IMG reference gene:2504154682; PFAM: S4 domain; FtsJ-like methyltransferase; TIGRFAM: hemolysin TlyA family protein.
       0.723
AEB10375.1
MgtC/SapB transporter; COGs: COG1285 membrane protein; InterPro IPR003416; KEGG: sfu:Sfum_3054 MgtC/SapB transporter; PFAM: MgtC/SapB transporter; SPTR: MgtC/SapB transporter; IMG reference gene:2504156118; PFAM: MgtC family.
  
 
 0.537
AEB08149.1
Sodium/hydrogen exchanger; COGs: COG0475 Kef-type K+ transport systems membrane components; InterPro IPR006153:IPR003148; KEGG: sfu:Sfum_2433 sodium/hydrogen exchanger; PFAM: Cation/H+ exchanger; Regulator of K+ conductance, N-terminal; SPTR: Sodium/hydrogen exchanger; IMG reference gene:2504153777; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
 
 0.503
atpE
ATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
   
 0.463
AEB09011.1
Two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR003593:IPR002078:IPR002197; KEGG: dbr:Deba_0845 two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver domain; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver domain; ATPase, AAA+ type, core; SPTR: Two component, sigma54 specific, transcript [...]
       0.458
speE
Spermine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
       0.458
AEB08045.1
EF hand repeat-containing protein; InterPro IPR002048:IPR018248; KEGG: plm:Plim_3206 sulfatase; PFAM: EF-hand; SMART: Calcium-binding EF-hand; SPTR: Sulfatase; IMG reference gene:2504153668; PFAM: EF hand.
   
 
 0.451
AEB10619.1
Long-chain-fatty-acid--CoA ligase., 1-acylglycerol-3-phosphate O-acyltransferase; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873:IPR006163:IPR002123; KEGG: aae:aq_999 long-chain-fatty-acid CoA ligase; PFAM: AMP-dependent synthetase/ligase; Phosphopantetheine-binding; Phospholipid/glycerol acyltransferase; PRIAM: Long-chain-fatty-acid--CoA ligase., 1-acylglycerol-3-phosphate O-acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Long-chain-fatty-acid CoA ligase; IMG reference gene:2504156381; PFAM: Phosphopantetheine attachment site; Acylt [...]
   
 0.400
Your Current Organism:
Desulfobacca acetoxidans
NCBI taxonomy Id: 880072
Other names: D. acetoxidans DSM 11109, Desulfobacca acetoxidans DSM 11109, Desulfobacca acetoxidans str. DSM 11109, Desulfobacca acetoxidans strain DSM 11109
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.