STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB09420.1Cupin 2 conserved barrel domain protein; InterPro IPR001387:IPR013096; KEGG: gme:Gmet_0901 XRE family transcriptional regulator; PFAM: Cupin 2, conserved barrel; Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Transcriptional regulator, XRE family; IMG reference gene:2504155111; PFAM: Cupin domain; Helix-turn-helix. (180 aa)    
Predicted Functional Partners:
AEB09418.1
COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644:IPR005170; KEGG: geo:Geob_3095 CBS domain containing protein; PFAM: Cystathionine beta-synthase, core; Transporter-associated domain; SMART: Cystathionine beta-synthase, core; SPTR: CBS domain containing protein; IMG reference gene:2504155109; PFAM: CBS domain; Transporter associated domain.
 
    0.787
AEB09419.1
S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
       0.777
AEB07994.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003018:IPR003661:IPR 003594:IPR001789:IPR008207:IPR013655:IPR013767; KEGG: ava:Ava_1029 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-3; PAS fold; GAF; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/ph [...]
  
  
 0.691
AEB08672.1
Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000595:IPR018060:IPR000005; KEGG: ote:Oter_4074 AraC family transcriptional regulator; PFAM: Cyclic nucleotide-binding domain; HTH transcriptional regulator, AraC; SMART: Helix-turn-helix, AraC type, DNA binding domain; Cyclic nucleotide-binding domain; SPTR: Transcriptional regulator, AraC family; IMG reference gene:2504154323; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; Cyclic nucleotide-binding domain.
 
 
 0.660
cobB
COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent histone deacetylase, silent information regulator Sir2; InterPro IPR003000; KEGG: sfu:Sfum_3557 silent information regulator protein Sir2; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: Silent information regulator protein Sir2; IMG reference gene:2504155309; PFAM: Sir2 family; Belongs to the sirtuin family. Class III subfamily.
  
    0.605
AEB08532.1
COGs: COG0077 Prephenate dehydratase; InterPro IPR002701:IPR020822:IPR001086:IPR002912; KEGG: glo:Glov_2150 chorismate mutase; PFAM: Prephenate dehydratase; Chorismate mutase, type II; Amino acid-binding ACT; SMART: Chorismate mutase; SPTR: Chorismate mutase; IMG reference gene:2504154179; PFAM: Prephenate dehydratase; ACT domain; Chorismate mutase type II.
  
  
 0.550
AEB09402.1
Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005:IPR018060; KEGG: bbe:BBR47_15160 putative transcriptional regulator; PFAM: HTH transcriptional regulator, AraC; SMART: Helix-turn-helix, AraC type, DNA binding domain; SPTR: Putative transcriptional regulator; IMG reference gene:2504155092; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family.
 
 
 0.509
AEB08635.1
Multi-sensor signal transduction multi-kinase; COGs: COG0591 Na+/proline symporter; InterProIPR003018:IPR000014:IPR001610:IPR003661:IPR 003594:IPR001734:IPR013767; KEGG: geo:Geob_2606 protein serine phosphatase with GAF(s) sensor(s); PFAM: ATPase-like, ATP-binding domain; GAF; Sodium/solute symporter; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; GAF; PAS; PAC motif; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Putative phytochrome sensor protein; T [...]
     
 0.507
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.501
AEB10320.1
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: pcl:Pcal_1387 aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase domain; SPTR: Aldehyde dehydrogenase; IMG reference gene:2504156059; PFAM: Aldehyde dehydrogenase family.
  
  
 0.480
Your Current Organism:
Desulfobacca acetoxidans
NCBI taxonomy Id: 880072
Other names: D. acetoxidans DSM 11109, Desulfobacca acetoxidans DSM 11109, Desulfobacca acetoxidans str. DSM 11109, Desulfobacca acetoxidans strain DSM 11109
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