STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB09589.1COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR002550:IPR000644:IPR005170; KEGG: tth:TTC0382 hemolysin-like protein; PFAM: Cystathionine beta-synthase, core; Domain of unknown function DUF21; Transporter-associated domain; SMART: Cystathionine beta-synthase, core; SPTR: Probable hemolysin-related protein/CBS domain containing protein; IMG reference gene:2504155298; PFAM: CBS domain; Domain of unknown function DUF21; Transporter associated domain. (431 aa)    
Predicted Functional Partners:
AEB09590.1
Protein of unknown function DUF21; COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR002550:IPR000644:IPR005170; KEGG: aar:Acear_0620 protein of unknown function DUF21; PFAM: Domain of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504155299; PFAM: CBS domain; Domain of unknown function DUF21; Transporter associated domain.
 
    
0.819
AEB09591.1
UPF0272 protein; COGs: COG1641 conserved hypothetical protein; HAMAP: Uncharacterised protein family UPF0272; InterPro IPR002822; KEGG: sfu:Sfum_2531 hypothetical protein; PFAM: Uncharacterised protein family UPF0272; SPTR: UPF0272 protein GM18DRAFT_2292; TIGRFAM: Uncharacterised protein family UPF0272; IMG reference gene:2504155300; PFAM: Protein of unknown function DUF111; TIGRFAM: TIGR00299 family protein; Belongs to the LarC family.
       0.773
lon-2
Anti-sigma H sporulation factor, LonB; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
       0.558
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.431
ybeY
Metalloprotease ybeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
  
 0.408
Your Current Organism:
Desulfobacca acetoxidans
NCBI taxonomy Id: 880072
Other names: D. acetoxidans DSM 11109, Desulfobacca acetoxidans DSM 11109, Desulfobacca acetoxidans str. DSM 11109, Desulfobacca acetoxidans strain DSM 11109
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.