STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB10039.1Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587:IPR000994; KEGG: sfu:Sfum_3318 peptidase M24; PFAM: Peptidase M24, structural domain; Creatinase; SPTR: Peptidase M24; IMG reference gene:2504155765; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain. (397 aa)    
Predicted Functional Partners:
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
   0.734
AEB10043.1
InterPro IPR000297; KEGG: pca:Pcar_1050 peptidyl-prolyl cis-trans isomerase; PFAM: Peptidyl-prolyl cis-trans isomerase, PpiC-type; SPTR: Putative uncharacterized protein; IMG reference gene:2504155769; PFAM: PPIC-type PPIASE domain.
     
 0.530
AEB10040.1
Lactate utilization protein B/C; COGs: COG1556 conserved hypothetical protein; InterPro IPR003741; KEGG: msv:Mesil_1094 protein of unknown function DUF162; PFAM: Domain of unknown function DUF162; SPTR: Putative uncharacterized protein; IMG reference gene:2504155766; PFAM: Uncharacterised ACR, YkgG family COG1556.
       0.516
AEB10041.1
Lactate utilization protein B/C; COGs: COG1139 conserved hypothetical protein containing a ferredoxin-like domain; InterPro IPR003741:IPR001450; KEGG: cag:Cagg_2719 iron-sulfur cluster binding protein; PFAM: Domain of unknown function DUF162; 4Fe-4S binding domain; SPTR: Iron-sulfur cluster binding protein; IMG reference gene:2504155767; PFAM: Uncharacterised ACR, YkgG family COG1556; TIGRFAM: iron-sulfur cluster-binding protein.
       0.485
AEB10042.1
KEGG: dma:DMR_17550 hypothetical membrane protein; SPTR: Hypothetical membrane protein; IMG reference gene:2504155768.
       0.485
AEB10044.1
COGs: COG1729 conserved hypothetical protein; KEGG: gsu:GSU0023 TPR domain protein; SPTR: TPR domain protein; IMG reference gene:2504155770; TIGRFAM: tol-pal system protein YbgF.
       0.479
AEB08011.1
Oligopeptide/dipeptide ABC transporter, ATPase subunit; COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterProIPR010066:IPR003593:IPR000515:IPR003439:IPR 013563; KEGG: dal:Dalk_0870 binding-protein-dependent transport systems inner membrane component; PFAM: ABC transporter-like; Binding-protein-dependent transport systems inner membrane component; Oligopeptide/dipeptide ABC transporter, C-terminal; PRIAM: Nickel-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; TIGRFAM: Oligopeptide/dipeptide ABC t [...]
  
  
 0.478
AEB08430.1
Pyruvate dehydrogenase (NADP(+))., 2-oxoglutarate synthase; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880:IPR019752:IPR001450:IPR011766; KEGG: cno:NT01CX_1854 pyruvate:ferredoxin (flavodoxin) oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; 4Fe-4S binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+))., 2-oxoglutarate synthase; SPTR: Pyruvate-flavodoxin oxid [...]
     
 0.459
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
  0.457
metG
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
   
 
 0.452
Your Current Organism:
Desulfobacca acetoxidans
NCBI taxonomy Id: 880072
Other names: D. acetoxidans DSM 11109, Desulfobacca acetoxidans DSM 11109, Desulfobacca acetoxidans str. DSM 11109, Desulfobacca acetoxidans strain DSM 11109
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.