STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ubiEUbiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (251 aa)    
Predicted Functional Partners:
AEB10264.1
UbiA prenyltransferase; COGs: COG1575 1 4-dihydroxy-2-naphthoate octaprenyltransferase; InterPro IPR000537; KEGG: tte:TTE2481 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 14-dihydroxy-2-naphthoate octaprenyltransferase; IMG reference gene:2504156002; PFAM: UbiA prenyltransferase family.
 
  
 0.917
AEB09262.1
Menaquinone biosynthesis decarboxylase, SCO4490 family; COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830:IPR022390; KEGG: dma:DMR_21400 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: Carboxylyase-related; SPTR: UbiD family decarboxylase; TIGRFAM: Menaquinone biosynthesis decarboxylase, SCO4490; Carboxylyase-related; IMG reference gene:2504154945; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: menaquinone biosynthesis decarboxylase, SCO4490 family; UbiD family decarboxylases; Belongs to the UbiD family.
 
  
 0.806
AEB09391.1
Trans-hexaprenyltranstransferase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: sfu:Sfum_1586 trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; PRIAM: Trans-hexaprenyltranstransferase; SPTR: Trans-hexaprenyltranstransferase; IMG reference gene:2504155080; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
  
 0.584
pdhA
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 
    
 0.493
AEB09952.1
Methyltransferase type 11; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: mac:MA2152 ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: Methyltransferase type 11; SPTR: Ubiquinone/menaquinone biosynthesis methyltransferase; IMG reference gene:2504155677; PFAM: Methyltransferase domain.
  
     0.455
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
  
 0.452
AEB10280.1
Amino acid adenylation domain protein; COGs: COG1020 Non-ribosomal peptide synthetase modules and related protein; InterProIPR001242:IPR000873:IPR006163:IPR001031:IPR 010071; KEGG: mar:MAE_60000 McnE protein; PFAM: AMP-dependent synthetase/ligase; Condensation domain; Phosphopantetheine-binding; Thioesterase; SPTR: OciC; TIGRFAM: Amino acid adenylation; IMG reference gene:2504156018; PFAM: Thioesterase domain; Phosphopantetheine attachment site; AMP-binding enzyme; Condensation domain; TIGRFAM: amino acid adenylation domain; Belongs to the ATP-dependent AMP-binding enzyme family.
     
 0.412
lipA
Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
    
 0.402
Your Current Organism:
Desulfobacca acetoxidans
NCBI taxonomy Id: 880072
Other names: D. acetoxidans DSM 11109, Desulfobacca acetoxidans DSM 11109, Desulfobacca acetoxidans str. DSM 11109, Desulfobacca acetoxidans strain DSM 11109
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