STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APF19524.1GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (732 aa)    
Predicted Functional Partners:
gmk
Gmk guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.947
Cabys_156
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.922
APF19723.1
Exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase.
  
 
 0.918
APF20517.1
ppGpp synthetase catalytic domain-containing protein (RelA/SpoT-type nucleotidyltransferase).
  
 
 0.915
ndk
Ndk nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.913
ndk-2
Ndk nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.913
Cabys_695
ppGpp synthetase catalytic domain-containing protein (RelA/SpoT-type nucleotidyltransferase).
    
 0.911
Cabys_116
Adenylyl cyclase CyaB, putative.
     
  0.900
Cabys_147
Adenylate cyclase.
     
  0.900
APF18808.1
Adenylate cyclase.
     
  0.900
Your Current Organism:
Caldithrix abyssi
NCBI taxonomy Id: 880073
Other names: C. abyssi DSM 13497, Caldithrix abyssi DSM 13497, Caldithrix abyssi LF13, Caldithrix abyssi str. DSM 13497, Caldithrix abyssi strain DSM 13497
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