STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
leuAleuA 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (521 aa)    
Predicted Functional Partners:
APF19380.1
Homoaconitate hydratase family protein/3-isopropylmalate dehydratase, large subunit/3-isopropylmalate dehydratase, small subunit.
 
 0.995
APF19947.1
3-isopropylmalate dehydratase, large subunit; Belongs to the aconitase/IPM isomerase family.
 
 0.992
APF19946.1
3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Belongs to the LeuD family.
 
 
 0.991
ilvD
ilvD dihydroxyacid dehydratase; Belongs to the IlvD/Edd family.
 
 
 0.991
APF19951.1
Acetolactate synthase, small subunit.
 
 
 0.969
Cabys_656
Branched-chain amino acid aminotransferase.
  
 0.962
APF19952.1
Acetolactate synthase, large subunit.
 
 
 0.961
Cabys_262
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
  
 
 0.950
APF18882.1
acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 
 0.947
Cabys_990
acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 
 0.947
Your Current Organism:
Caldithrix abyssi
NCBI taxonomy Id: 880073
Other names: C. abyssi DSM 13497, Caldithrix abyssi DSM 13497, Caldithrix abyssi LF13, Caldithrix abyssi str. DSM 13497, Caldithrix abyssi strain DSM 13497
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