STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cabys_863ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. (822 aa)    
Predicted Functional Partners:
dnaK
dnaK molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.965
clpP
clpP ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
 
 
 0.959
grpE
grpE molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds o [...]
  
 
 0.849
htpG
htpG molecular chaperone HtpG; Molecular chaperone. Has ATPase activity.
  
 
 0.813
APF20023.1
Hypothetical protein.
 
  
 0.786
APF20506.1
Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family.
  
 
 0.716
APF20507.1
Molecular chaperone IbpA, HSP20 family; Belongs to the small heat shock protein (HSP20) family.
  
 
 0.716
APF20508.1
HSP20 family protein; Belongs to the small heat shock protein (HSP20) family.
  
 
 0.716
hSP20
HSP20 family protein; Belongs to the small heat shock protein (HSP20) family.
  
 
 0.716
APF20505.1
Curved DNA-binding protein.
  
 
 0.703
Your Current Organism:
Caldithrix abyssi
NCBI taxonomy Id: 880073
Other names: C. abyssi DSM 13497, Caldithrix abyssi DSM 13497, Caldithrix abyssi LF13, Caldithrix abyssi str. DSM 13497, Caldithrix abyssi strain DSM 13497
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