Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KOY63381.1Carboxy-terminal protease; Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; Derived by automated computational analysis using gene prediction method: Protein Homology. (683 aa)    
Predicted Functional Partners:
nlpI
Lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 
 0.908
spr
Lipoprotein Spr; Mutational suppressor of prc thermosensitivity; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.888
proQ
Prop expression regulator; Affects solute and DNA transport through an unknown mechanism; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.875
KOY60728.1
Low calcium response locus protein H; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.783
thrA
Aspartate kinase; Multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.729
KOY60657.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.719
KOY63383.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.706
metL
Aspartate kinase; Multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.684
KOY63358.1
Endopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.682
envC
Peptidase M37; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.661
Your Current Organism:
Photorhabdus heterorhabditis
NCBI taxonomy Id: 880156
Other names: ATCC BAA-2479, DSM 25263, P. heterorhabditis, Photorhabdus heterorhabditis Ferreira et al. 2014, Photorhabdus sp. Q614, Photorhabdus sp. Q614(2009), Photorhabdus sp. SF41, Photorhabdus sp. SF783, strain SF41
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