Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hupADNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (90 aa)    
Predicted Functional Partners:
rplS
50S ribosomal protein L19; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.803
dnaA
Chromosomal replication initiation protein; Binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.680
rplA
50S ribosomal protein L1; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.659
stlE
Acyl carrier protein; Carries the fatty acid chain in fatty acid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.653
acpP
Acyl carrier protein; Carries the fatty acid chain in fatty acid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.653
ihfA
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
0.648
KOY60372.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.617
rpsO
30S ribosomal protein S15; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.545
rpsT
30S ribosomal protein S20; Binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.505
KOY60374.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.504
Your Current Organism:
Photorhabdus heterorhabditis
NCBI taxonomy Id: 880156
Other names: ATCC BAA-2479, DSM 25263, P. heterorhabditis, Photorhabdus heterorhabditis Ferreira et al. 2014, Photorhabdus sp. Q614, Photorhabdus sp. Q614(2009), Photorhabdus sp. SF41, Photorhabdus sp. SF783, strain SF41
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.