Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KOY60365.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)    
Predicted Functional Partners:
aroE
Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.831
KOY60368.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.829
tsaC
tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Involved in the biosynthesis of the threonylcarbamoyladenosine (t6A) residue at position 37 of ANN-decoding tRNAs; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.828
dprA
DNA processing protein DprA; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.725
fdxH
Formate dehydrogenase; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.
   
    0.712
KOY61531.1
DNA topoisomerase III; Decatenates replicating daughter chromosomes; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.598
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.589
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.570
fmt
methionyl-tRNA formyltransferase; Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.529
leuS
leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; Derived by automated computational [...]
   
 
 0.526
Your Current Organism:
Photorhabdus heterorhabditis
NCBI taxonomy Id: 880156
Other names: ATCC BAA-2479, DSM 25263, P. heterorhabditis, Photorhabdus heterorhabditis Ferreira et al. 2014, Photorhabdus sp. Q614, Photorhabdus sp. Q614(2009), Photorhabdus sp. SF41, Photorhabdus sp. SF783, strain SF41
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