STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KOY60365.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)    
Predicted Functional Partners:
tsaC
tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Involved in the biosynthesis of the threonylcarbamoyladenosine (t6A) residue at position 37 of ANN-decoding tRNAs; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.815
KOY60368.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.809
aroE
Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.806
fdxH
Formate dehydrogenase; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.
   
    0.708
dprA
DNA processing protein DprA; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.693
KOY61734.1
Single-stranded DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.636
KOY61531.1
DNA topoisomerase III; Decatenates replicating daughter chromosomes; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.605
leuS
leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; Derived by automated computational [...]
   
 
 0.595
rpoA
DNA-directed RNA polymerase subunit alpha; Catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.533
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.488
Your Current Organism:
Photorhabdus heterorhabditis
NCBI taxonomy Id: 880156
Other names: ATCC BAA-2479, DSM 25263, P. heterorhabditis, Photorhabdus heterorhabditis Ferreira et al. 2014, Photorhabdus sp. Q614, Photorhabdus sp. Q614(2009), Photorhabdus sp. SF41, Photorhabdus sp. SF783, strain SF41
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