STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D8QNH0_SELMLUbiquitin-related modifier 1; Belongs to the URM1 family. (87 aa)    
Predicted Functional Partners:
MOCS3
Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]
    
 0.982
D8SG67_SELML
Rhodanese domain-containing protein.
    
 0.982
D8RDQ5_SELML
Ubiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress spec [...]
  
  
 
0.900
D8R977_SELML
Protein kinase domain-containing protein.
    
 0.881
D8RBF4_SELML
Protein kinase domain-containing protein.
    
 0.881
D8RCF6_SELML
CaMKII_AD domain-containing protein.
    
 0.881
D8RPG6_SELML
Protein kinase domain-containing protein.
    
 0.881
D8SM74_SELML
Protein kinase domain-containing protein.
    
 0.881
D8T4W6_SELML
CaMKII_AD domain-containing protein.
    
 0.881
D8R6I1_SELML
Guanylate kinase-like domain-containing protein.
    
 0.845
Your Current Organism:
Selaginella moellendorffii
NCBI taxonomy Id: 88036
Other names: S. moellendorffii, Selaginella moellendorffii Hieron., Selaginella moellendorfii
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.