node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
D8RE52_SELML | NCS6 | D8RE52 | D8RDD4 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. | 0.571 |
D8RE52_SELML | NCS6-2 | D8RE52 | D8RSC3 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. | 0.571 |
D8RFX1_SELML | D8RRI5_SELML | D8RFX1 | D8RRI5 | Uncharacterized protein. | ATP_bind_3 domain-containing protein; Belongs to the CTU2/NCS2 family. | 0.652 |
D8RFX1_SELML | D8RXE4_SELML | D8RFX1 | D8RXE4 | Uncharacterized protein. | ATP_bind_3 domain-containing protein; Belongs to the CTU2/NCS2 family. | 0.652 |
D8RFX1_SELML | NCS6 | D8RFX1 | D8RDD4 | Uncharacterized protein. | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. | 0.456 |
D8RFX1_SELML | NCS6-2 | D8RFX1 | D8RSC3 | Uncharacterized protein. | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. | 0.456 |
D8RRI5_SELML | D8RFX1_SELML | D8RRI5 | D8RFX1 | ATP_bind_3 domain-containing protein; Belongs to the CTU2/NCS2 family. | Uncharacterized protein. | 0.652 |
D8RRI5_SELML | D8RXE4_SELML | D8RRI5 | D8RXE4 | ATP_bind_3 domain-containing protein; Belongs to the CTU2/NCS2 family. | ATP_bind_3 domain-containing protein; Belongs to the CTU2/NCS2 family. | 0.900 |
D8RRI5_SELML | D8SG67_SELML | D8RRI5 | D8SG67 | ATP_bind_3 domain-containing protein; Belongs to the CTU2/NCS2 family. | Rhodanese domain-containing protein. | 0.567 |
D8RRI5_SELML | D8SPC4_SELML | D8RRI5 | D8SPC4 | ATP_bind_3 domain-containing protein; Belongs to the CTU2/NCS2 family. | Uncharacterized protein. | 0.652 |
D8RRI5_SELML | MOCS3 | D8RRI5 | D8R5Z7 | ATP_bind_3 domain-containing protein; Belongs to the CTU2/NCS2 family. | Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] | 0.567 |
D8RRI5_SELML | NCS6 | D8RRI5 | D8RDD4 | ATP_bind_3 domain-containing protein; Belongs to the CTU2/NCS2 family. | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. | 0.976 |
D8RRI5_SELML | NCS6-2 | D8RRI5 | D8RSC3 | ATP_bind_3 domain-containing protein; Belongs to the CTU2/NCS2 family. | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. | 0.976 |
D8RXE4_SELML | D8RFX1_SELML | D8RXE4 | D8RFX1 | ATP_bind_3 domain-containing protein; Belongs to the CTU2/NCS2 family. | Uncharacterized protein. | 0.652 |
D8RXE4_SELML | D8RRI5_SELML | D8RXE4 | D8RRI5 | ATP_bind_3 domain-containing protein; Belongs to the CTU2/NCS2 family. | ATP_bind_3 domain-containing protein; Belongs to the CTU2/NCS2 family. | 0.900 |
D8RXE4_SELML | D8SG67_SELML | D8RXE4 | D8SG67 | ATP_bind_3 domain-containing protein; Belongs to the CTU2/NCS2 family. | Rhodanese domain-containing protein. | 0.567 |
D8RXE4_SELML | D8SPC4_SELML | D8RXE4 | D8SPC4 | ATP_bind_3 domain-containing protein; Belongs to the CTU2/NCS2 family. | Uncharacterized protein. | 0.652 |
D8RXE4_SELML | MOCS3 | D8RXE4 | D8R5Z7 | ATP_bind_3 domain-containing protein; Belongs to the CTU2/NCS2 family. | Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] | 0.567 |
D8RXE4_SELML | NCS6 | D8RXE4 | D8RDD4 | ATP_bind_3 domain-containing protein; Belongs to the CTU2/NCS2 family. | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. | 0.976 |
D8RXE4_SELML | NCS6-2 | D8RXE4 | D8RSC3 | ATP_bind_3 domain-containing protein; Belongs to the CTU2/NCS2 family. | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. | 0.976 |