STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D8RWM2_SELMLDeacetylase sirtuin-type domain-containing protein. (259 aa)    
Predicted Functional Partners:
D8R2U1_SELML
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.788
D8QVP4_SELML
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
     
 0.602
D8SA97_SELML
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
     
 0.602
D8SH69_SELML
Deacetylase sirtuin-type domain-containing protein.
  
   
0.588
D8QR38_SELML
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
  
 
 0.527
D8R7U6_SELML
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
  
 
 0.527
D8SIQ7_SELML
3'-5' exonuclease domain-containing protein.
  
 
 0.527
D8SWC2_SELML
3'-5' exonuclease domain-containing protein.
  
 
 0.527
D8RBS5_SELML
BPL/LPL catalytic domain-containing protein.
  
 
  0.522
D8RXV4_SELML
BPL/LPL catalytic domain-containing protein.
  
 
  0.522
Your Current Organism:
Selaginella moellendorffii
NCBI taxonomy Id: 88036
Other names: S. moellendorffii, Selaginella moellendorffii Hieron., Selaginella moellendorfii
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