STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiCUnannotated protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (514 aa)    
Predicted Functional Partners:
thiD
Unannotated protein.
 
 
 0.987
thiE_1
Unannotated protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 
 0.975
thiH
Unannotated protein.
 
  
 0.829
GCA_000427365_00928
Unannotated protein; Belongs to the FPP/GGPP synthase family.
  
  
 0.797
thiE_2
Unannotated protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 
 0.754
thiM
Unannotated protein; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
  
 
 0.699
GCA_000427365_01316
Unannotated protein.
  
 
 0.688
GCA_000427365_02030
Unannotated protein.
  
 
 0.688
GCA_000427365_00266
Unannotated protein.
  
  
 0.626
GCA_000427365_00515
Unannotated protein.
  
  
 0.626
Your Current Organism:
Rikenella microfusus
NCBI taxonomy Id: 880526
Other names: R. microfusus DSM 15922, Rikenella microfusus ATCC 29728, Rikenella microfusus DSM 15922, Rikenella microfusus JCM 2053, Rikenella microfusus str. DSM 15922, Rikenella microfusus strain DSM 15922
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