Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hisDHistidinol dehydrogenase. (437 aa)    
Predicted Functional Partners:
hisB
Imidazoleglycerol-phosphate dehydratase.
  
 0.998
EIO_2330
Imidazoleglycerol phosphate synthase, cyclase subunit.
  
 0.996
hisC
Histidinol-phosphate aminotransferase.
  
 0.991
EIO_2328
Imidazole glycerol phosphate synthase.
 
  
 0.987
hisI
phosphoribosyl-AMP cyclohydrolase.
 
  
 0.986
hisA
1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase.
 
  
 0.985
EIO_2209
Histidinol-phosphate aminotransferase.
  
 0.981
hisG
ATP phosphoribosyltransferase.
 
  
 0.978
hisE
phosphoribosyl-ATP diphosphatase.
 
  
 0.975
hisZ
ATP phosphoribosyltransferase regulatory subunit.
 
  
 0.927
Your Current Organism:
Ketogulonicigenium vulgare
NCBI taxonomy Id: 880591
Other names: K. vulgare Y25, Ketogulonicigenium vulgare Y25, Ketogulonicigenium vulgare str. Y25, Ketogulonicigenium vulgare strain Y25
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