Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
glyASerine hydroxymethyltransferase. (428 aa)    
Predicted Functional Partners:
EIO_1627
Glycine dehydrogenase.
 
 
 0.999
EIO_1625
Glycine cleavage system T protein.
 
 0.998
EIO_1626
Glycine cleavage system H protein.
  
 
 0.994
EIO_1282
Phosphoribosylglycinamide formyltransferase.
  
 0.966
folD
Bifunctional protein FolD 2.
  
 0.964
EIO_2070
Methylenetetrahydrofolate dehydrogenase (NADP(+)).
  
 0.961
EIO_2073
FolD bifunctional protein.
  
 0.961
metF
metF-like protein.
  
 
 0.952
EIO_1198
5-aminolevulinate synthase.
 
 
 0.949
metH
Probable 5-methyltetrahydrofolate--homocysteine methyltransferase.
     
 0.943
Your Current Organism:
Ketogulonicigenium vulgare
NCBI taxonomy Id: 880591
Other names: K. vulgare Y25, Ketogulonicigenium vulgare Y25, Ketogulonicigenium vulgare str. Y25, Ketogulonicigenium vulgare strain Y25
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