Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEF95572.1Phosphoadenosine phosphosulfate reductase; KEGG: mvn:Mevan_0248 hypothetical protein; PFAM: Phosphoadenosine phosphosulphate reductase; Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase. (480 aa)    
Predicted Functional Partners:
AEF95996.1
TIGRFAM: Uroporphyrin-III C-methyltransferase, C-terminal; KEGG: mfs:MFS40622_1215 uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole methylase; Belongs to the precorrin methyltransferase family.
 
  
 0.767
AEF96222.1
KEGG: mmz:MmarC7_1694 hypothetical protein.
 
     0.718
hcp
Hydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
  
  
 0.698
AEF95882.1
KEGG: mae:Maeo_0300 molybdate ABC transporter, inner membrane subunit; TIGRFAM: Molybdate ABC transporter, permease protein; PFAM: Binding-protein-dependent transport systems inner membrane component.
  
  
 0.673
AEF96005.1
ABC-type transporter, integral membrane subunit; KEGG: mmp:MMP1519 anion transport system permease; manually curated; PFAM: Binding-protein-dependent transport systems inner membrane component.
  
  
 0.673
AEF95684.1
KEGG: mvu:Metvu_1003 serine/threonine protein kinase with TPR repeats; PFAM: Serine/threonine-protein kinase-like domain; SMART: Serine/threonine-protein kinase domain; Tyrosine-protein kinase, catalytic domain.
   
 
 0.641
AEF95820.1
TIM-barrel protein; TIGRFAM: tRNA-dihydrouridine synthase, TIM-barrel, NifR3-related; KEGG: mfs:MFS40622_0138 TIM-barrel protein.
   
 
 0.618
cbiX
Sirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin.
  
  
 0.576
AEF97016.1
TIGRFAM: Sirohaem synthase, N-terminal; KEGG: mmx:MmarC6_0858 siroheme synthase.
  
  
 0.573
AEF95573.1
PFAM: ThiamineS; KEGG: mmz:MmarC7_0602 thiamineS protein.
     
 0.553
Your Current Organism:
Methanotorris igneus
NCBI taxonomy Id: 880724
Other names: M. igneus Kol 5, Methanotorris igneus DSM 5666, Methanotorris igneus JCM 11834, Methanotorris igneus Kol 5, Methanotorris igneus str. Kol 5, Methanotorris igneus strain Kol 5
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