STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rgyReverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family. (1119 aa)    
Predicted Functional Partners:
AEF95993.1
PFAM: NADPH-dependent FMN reductase; KEGG: mja:MJ_0731 iron-sulfur flavoprotein.
      
 0.735
fbp
Protein of unknown function DUF100; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
  
   
 0.674
AEF96846.1
PFAM: Circadian clock protein KaiC/DNA repair protein RadA; TIGRFAM: Uncharacterised protein family UPF0273, KiaC-like; HAMAP: Uncharacterised protein family UPF0273, KiaC-like; KEGG: mja:MJ_1359 hypothetical protein; Belongs to the UPF0273 family.
 
     0.669
AEF96243.1
KEGG: tba:TERMP_00900 hypothetical protein; PFAM: THUMP; SMART: THUMP.
  
   
 0.593
dnaG
UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
      
 0.581
taw3
tRNA wybutosine-synthesizing protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family.
 
     0.555
AEF96926.1
HAMAP: Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase; KEGG: mfs:MFS40622_0646 hypothetical protein; Belongs to the UPF0282 family.
  
     0.451
leuS
TIGRFAM: Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic; KEGG: mfs:MFS40622_1044 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
     0.419
AEF96135.1
KEGG: mfs:MFS40622_1672 conserved hypothetical cytosolic protein.
 
     0.402
Your Current Organism:
Methanotorris igneus
NCBI taxonomy Id: 880724
Other names: M. igneus Kol 5, Methanotorris igneus DSM 5666, Methanotorris igneus JCM 11834, Methanotorris igneus Kol 5, Methanotorris igneus str. Kol 5, Methanotorris igneus strain Kol 5
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