Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mptDProtein of unknown function DUF381; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family. (126 aa)    
Predicted Functional Partners:
mptE
Protein of unknown function DUF115; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family.
 
  
 0.974
AEF96145.1
Archaeoflavoprotein, MJ0208 family; KEGG: mja:MJ_0208 4Fe-4S iron-sulfur protein; TIGRFAM: Archaeoflavoprotein MJ0208; PFAM: Flavoprotein; 4Fe-4S binding domain.
 
     0.660
AEF96556.1
UPF0179 protein; KEGG: mmq:MmarC5_1728 hypothetical protein; HAMAP: Uncharacterised protein family UPF0179; PFAM: Uncharacterised protein family UPF0179; Belongs to the UPF0179 family.
  
     0.643
mptA
Protein of unknown function DUF198; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
 
   
 0.637
AEF96541.1
Hypothetical protein; Manually curated; KEGG: mae:Maeo_0740 hypothetical protein.
       0.633
AEF97213.1
TIGRFAM: Conserved hypothetical protein CHP01210; PFAM: Radical SAM; KEGG: mja:MJ_0550 hypothetical protein; SMART: Elongator protein 3/MiaB/NifB.
  
     0.615
AEF96272.1
Regulatory protein Crp; SMART: HTH transcriptional regulator, Crp; KEGG: mvu:Metvu_1066 transcriptional regulator, MarR family.
  
     0.600
AEF96542.1
KEGG: mvn:Mevan_1023 hypothetical protein.
       0.590
AEF97309.1
Protein of unknown function UPF0058; PFAM: Uncharacterised protein family UPF0058; KEGG: mvn:Mevan_0597 hypothetical protein.
  
   
 0.590
AEF95739.1
HAMAP: HTH transcriptional regulator, cro/C1-type DNA-binding domain-containing; PFAM: Helix-turn-helix type 3; KEGG: mja:MJ_1164 hypothetical protein; SMART: Helix-turn-helix type 3.
  
     0.583
Your Current Organism:
Methanotorris igneus
NCBI taxonomy Id: 880724
Other names: M. igneus Kol 5, Methanotorris igneus DSM 5666, Methanotorris igneus JCM 11834, Methanotorris igneus Kol 5, Methanotorris igneus str. Kol 5, Methanotorris igneus strain Kol 5
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