Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEF96650.1Radical SAM domain protein; KEGG: mja:MJ_0597 hypothetical protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; Biotin/thiamin synthesis-associated protein. (365 aa)    
Predicted Functional Partners:
bioD
Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
  
  
 0.785
bioA
Adenosylmethionine--8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
  
  
 0.751
AEF96805.1
8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
  
  
 0.711
bioW
6-carboxyhexanoate/CoA ligase; Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.
  
  
 0.699
AEF96501.1
Brix domain-containing ribosomal biogenesis protein; Probably involved in the biogenesis of the ribosome.
 
     0.696
thi4-2
Thiazole biosynthetic enzyme; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
     
 0.689
AEF97329.1
PFAM: Oligosaccharyl transferase, STT3 subunit; KEGG: mfs:MFS40622_0538 oligosaccharyl transferase STT3 subunit.
 
     0.683
AEF96829.1
KEGG: mfs:MFS40622_1578 hypothetical protein.
       0.642
rpl18a
HAMAP: Ribosomal protein LX; KEGG: mmz:MmarC7_1057 50S ribosomal protein LX.
     
 0.639
AEF96631.1
TIGRFAM: Pyridoxal phosphate-dependent transferase, archaea; KEGG: mfs:MFS40622_0115 pyridoxal phosphate enzyme.
  
   
 0.635
Your Current Organism:
Methanotorris igneus
NCBI taxonomy Id: 880724
Other names: M. igneus Kol 5, Methanotorris igneus DSM 5666, Methanotorris igneus JCM 11834, Methanotorris igneus Kol 5, Methanotorris igneus str. Kol 5, Methanotorris igneus strain Kol 5
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