STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Coexpression
Experiments
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[Homology]
Score
AEF97195.1Precorrin-6x reductase; KEGG: mja:MJ_0552 cobalamin biosynthesis protein CbiJ; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobK/CbiJ, precorrin-6x reductase; PFAM: Cobalamin (vitamin B12) biosynthesis CobK/CbiJ, precorrin-6x reductase. (254 aa)    
Predicted Functional Partners:
cbiT
cobalt-precorrin-6Y C(15)-methyltransferase (decarboxylating); Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.
 
 0.998
AEF96010.1
precorrin-3B C17-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; KEGG: mae:Maeo_0830 precorrin-3B C17-methyltransferase; PFAM: Tetrapyrrole methylase.
  
 0.996
cbiD
cobalt-precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
 
 0.993
AEF96724.1
Precorrin-2 C20-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobI/CbiL, precorrin-2 C20-methyltransferase, core; KEGG: mfs:MFS40622_1405 precorrin-2 C20-methyltransferase; PFAM: Tetrapyrrole methylase.
 
  
 0.984
AEF96209.1
PFAM: Cobalamin (vitamin B12) biosynthesis CbiG, core; KEGG: mae:Maeo_0036 cobalamin (vitamin B12) biosynthesis CbiG protein.
  
 0.976
AEF97230.1
Precorrin-8X methylmutase CbiC/CobH; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; KEGG: mja:MJ_0930 precorrin-8X methylmutase.
 
  
 0.967
AEF96956.1
Precorrin-4 C11-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase, core; Uroporphyrin-III C-methyltransferase, C-terminal; KEGG: mja:MJ_1578 cobalamin biosynthesis precorrin-3 methylase CbiF; PFAM: Tetrapyrrole methylase.
 
  
 0.952
cobS
Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
  
  
 0.900
AEF96685.1
PFAM: Cobyrinic acid a,c-diamide synthase; CobB/CobQ-like glutamine amidotransferase; KEGG: mae:Maeo_1143 cobyrinic acid a,c-diamide synthase.
 
  
 0.884
cbiA
Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
 
  
 0.856
Your Current Organism:
Methanotorris igneus
NCBI taxonomy Id: 880724
Other names: M. igneus Kol 5, Methanotorris igneus DSM 5666, Methanotorris igneus JCM 11834, Methanotorris igneus Kol 5, Methanotorris igneus str. Kol 5, Methanotorris igneus strain Kol 5
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