node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DVU_0156 | ligA | DVU_0156 | DVU_1608 | ATP-dependent DNA helicase, UvrD/REP family; Identified by match to protein family HMM PF00580. | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.706 |
DVU_0156 | recA | DVU_0156 | DVU_1090 | ATP-dependent DNA helicase, UvrD/REP family; Identified by match to protein family HMM PF00580. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.857 |
DVU_0156 | recR | DVU_0156 | DVU_3200 | ATP-dependent DNA helicase, UvrD/REP family; Identified by match to protein family HMM PF00580. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.434 |
DVU_0156 | uvrA | DVU_0156 | DVU_1987 | ATP-dependent DNA helicase, UvrD/REP family; Identified by match to protein family HMM PF00580. | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.757 |
DVU_0156 | uvrB | DVU_0156 | DVU_1605 | ATP-dependent DNA helicase, UvrD/REP family; Identified by match to protein family HMM PF00580. | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.904 |
DVU_0156 | uvrC | DVU_0156 | DVU_0801 | ATP-dependent DNA helicase, UvrD/REP family; Identified by match to protein family HMM PF00580. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.817 |
DVU_0453 | ligA | DVU_0453 | DVU_1608 | ATP-dependent DNA helicase, UvrD/REP family; Identified by match to protein family HMM PF00580. | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.736 |
DVU_0453 | recA | DVU_0453 | DVU_1090 | ATP-dependent DNA helicase, UvrD/REP family; Identified by match to protein family HMM PF00580. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.878 |
DVU_0453 | uvrA | DVU_0453 | DVU_1987 | ATP-dependent DNA helicase, UvrD/REP family; Identified by match to protein family HMM PF00580. | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.631 |
DVU_0453 | uvrB | DVU_0453 | DVU_1605 | ATP-dependent DNA helicase, UvrD/REP family; Identified by match to protein family HMM PF00580. | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.852 |
DVU_0453 | uvrC | DVU_0453 | DVU_0801 | ATP-dependent DNA helicase, UvrD/REP family; Identified by match to protein family HMM PF00580. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.760 |
DVU_1606 | DVU_1607 | DVU_1606 | DVU_1607 | Potassium uptake protein, TrkA family; Identified by similarity to OMNI:NTL01SS00580; match to protein family HMM PF02080; match to protein family HMM PF02254. | Hypothetical protein; Identified by Glimmer2; putative. | 0.776 |
DVU_1606 | ligA | DVU_1606 | DVU_1608 | Potassium uptake protein, TrkA family; Identified by similarity to OMNI:NTL01SS00580; match to protein family HMM PF02080; match to protein family HMM PF02254. | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.663 |
DVU_1606 | uvrB | DVU_1606 | DVU_1605 | Potassium uptake protein, TrkA family; Identified by similarity to OMNI:NTL01SS00580; match to protein family HMM PF02080; match to protein family HMM PF02254. | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.810 |
DVU_1607 | DVU_1606 | DVU_1607 | DVU_1606 | Hypothetical protein; Identified by Glimmer2; putative. | Potassium uptake protein, TrkA family; Identified by similarity to OMNI:NTL01SS00580; match to protein family HMM PF02080; match to protein family HMM PF02254. | 0.776 |
DVU_1607 | ligA | DVU_1607 | DVU_1608 | Hypothetical protein; Identified by Glimmer2; putative. | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.624 |
DVU_1607 | uvrB | DVU_1607 | DVU_1605 | Hypothetical protein; Identified by Glimmer2; putative. | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.780 |
ligA | DVU_0156 | DVU_1608 | DVU_0156 | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | ATP-dependent DNA helicase, UvrD/REP family; Identified by match to protein family HMM PF00580. | 0.706 |
ligA | DVU_0453 | DVU_1608 | DVU_0453 | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | ATP-dependent DNA helicase, UvrD/REP family; Identified by match to protein family HMM PF00580. | 0.736 |
ligA | DVU_1606 | DVU_1608 | DVU_1606 | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | Potassium uptake protein, TrkA family; Identified by similarity to OMNI:NTL01SS00580; match to protein family HMM PF02080; match to protein family HMM PF02254. | 0.663 |