node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DVU_1349 | cmk | DVU_1349 | DVU_1028 | Geranylgeranyl diphosphate synthase; Identified by similarity to GP:5631295; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | Cytidylate kinase; Identified by similarity to SP:P23863; match to protein family HMM PF02224; match to protein family HMM TIGR00017. | 0.551 |
DVU_1349 | dxr | DVU_1349 | DVU_0866 | Geranylgeranyl diphosphate synthase; Identified by similarity to GP:5631295; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.536 |
DVU_1349 | dxs | DVU_1349 | DVU_1350 | Geranylgeranyl diphosphate synthase; Identified by similarity to GP:5631295; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.938 |
DVU_1349 | idi | DVU_1349 | DVU_1679 | Geranylgeranyl diphosphate synthase; Identified by similarity to GP:5631295; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | Isopentenyl-diphosphate delta-isomerase; Identified by match to protein family HMM PF00293. | 0.925 |
DVU_1349 | ispD | DVU_1349 | DVU_1454 | Geranylgeranyl diphosphate synthase; Identified by similarity to GP:5631295; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. | 0.559 |
DVU_1349 | ispE | DVU_1349 | DVU_1576 | Geranylgeranyl diphosphate synthase; Identified by similarity to GP:5631295; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.406 |
DVU_1349 | ispG | DVU_1349 | DVU_1344 | Geranylgeranyl diphosphate synthase; Identified by similarity to GP:5631295; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.752 |
DVU_1349 | ispH | DVU_1349 | DVU_0055 | Geranylgeranyl diphosphate synthase; Identified by similarity to GP:5631295; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. | 0.952 |
RpsA | cmk | DVU_1469 | DVU_1028 | Ribosomal protein S1, putative; Identified by similarity to SP:P02349; match to protein family HMM PF00575. | Cytidylate kinase; Identified by similarity to SP:P23863; match to protein family HMM PF02224; match to protein family HMM TIGR00017. | 0.900 |
RpsA | ispD | DVU_1469 | DVU_1454 | Ribosomal protein S1, putative; Identified by similarity to SP:P02349; match to protein family HMM PF00575. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. | 0.538 |
RpsA | ispH | DVU_1469 | DVU_0055 | Ribosomal protein S1, putative; Identified by similarity to SP:P02349; match to protein family HMM PF00575. | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. | 0.909 |
RpsA | rpsA | DVU_1469 | DVU_3150 | Ribosomal protein S1, putative; Identified by similarity to SP:P02349; match to protein family HMM PF00575. | Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 0.918 |
cmk | DVU_1349 | DVU_1028 | DVU_1349 | Cytidylate kinase; Identified by similarity to SP:P23863; match to protein family HMM PF02224; match to protein family HMM TIGR00017. | Geranylgeranyl diphosphate synthase; Identified by similarity to GP:5631295; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | 0.551 |
cmk | RpsA | DVU_1028 | DVU_1469 | Cytidylate kinase; Identified by similarity to SP:P23863; match to protein family HMM PF02224; match to protein family HMM TIGR00017. | Ribosomal protein S1, putative; Identified by similarity to SP:P02349; match to protein family HMM PF00575. | 0.900 |
cmk | ispD | DVU_1028 | DVU_1454 | Cytidylate kinase; Identified by similarity to SP:P23863; match to protein family HMM PF02224; match to protein family HMM TIGR00017. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. | 0.505 |
cmk | ispH | DVU_1028 | DVU_0055 | Cytidylate kinase; Identified by similarity to SP:P23863; match to protein family HMM PF02224; match to protein family HMM TIGR00017. | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. | 0.909 |
cmk | rpsA | DVU_1028 | DVU_3150 | Cytidylate kinase; Identified by similarity to SP:P23863; match to protein family HMM PF02224; match to protein family HMM TIGR00017. | Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 0.920 |
dxr | DVU_1349 | DVU_0866 | DVU_1349 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Geranylgeranyl diphosphate synthase; Identified by similarity to GP:5631295; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | 0.536 |
dxr | dxs | DVU_0866 | DVU_1350 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.995 |
dxr | ispD | DVU_0866 | DVU_1454 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. | 0.995 |