close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DVU_0191Conserved hypothetical protein; Identified by similarity to OMNI:CC3049. (519 aa)    
Predicted Functional Partners:
DVU_0194
Terminase, large subunit, putative; Identified by similarity to GP:6723224.
 
    0.880
DVU_0192
Adenine specific DNA methyltransferase, putative; Identified by match to protein family HMM PF01555; match to protein family HMM PF02195; Belongs to the N(4)/N(6)-methyltransferase family.
  
    0.870
DVU_2881
Phage-plasmid primase, P4 family; Identified by match to protein family HMM PF03288; match to protein family HMM TIGR01613.
 
    0.859
DVU_2592
Hypothetical protein; Identified by Glimmer2; putative.
   
    0.802
DVU_0189
Phage-plasmid primase, P4 family; Identified by match to protein family HMM PF03288; match to protein family HMM TIGR01613.
 
    0.800
DVU_2876
Terminase, large subunit, putative; Identified by similarity to GP:13361094.
  
    0.783
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.773
DVU_2185
Terminase, large subunit, putative.
  
    0.773
DVU_2591
Tail fiber assembly protein, putative.
   
    0.759
DVU_0214
tail/DNA circulation protein, putative; Identified by similarity to GP:19483753.
   
    0.737
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.