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hisH protein (Desulfovibrio vulgaris Hildenborough) - STRING interaction network
"hisH" - Imidazole glycerol phosphate synthase subunit HisH in Desulfovibrio vulgaris Hildenborough
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Known Interactions
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Predicted Interactions
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textmining
co-expression
protein homology
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hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (213 aa)    
Predicted Functional Partners:
hisF
Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit; Belongs to the HisA/HisF family (259 aa)
  0.999
hisA
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Identified by similarity to SP-O35006; match to protein family HMM PF00977 (249 aa)
 
  0.999
hisB
Imidazoleglycerol-phosphate dehydratase; Identified by similarity to SP-O34683; match to protein family HMM PF00475 (198 aa)
 
 
  0.998
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N’-(5’-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity; Belongs to the ATP phosphoribosyltransferase family. Long subfamily (293 aa)
 
   
  0.981
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (436 aa)
 
   
  0.977
hisC
Histidinol-phosphate aminotransferase; Identified by similarity to SP-P17731; match to protein family HMM PF00155; match to protein family HMM TIGR01141 (373 aa)
 
   
  0.971
hisI
Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP (126 aa)
 
   
  0.967
DVU_1059
annotation not available (390 aa)
 
   
  0.826
purB
Adenylosuccinate lyase; Identified by similarity to SP-P12047; match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily (430 aa)
   
 
    0.818
DVU_3206
Phosphoribosylaminoimidazolecarboxamide formyltransferase, putative; Identified by similarity to SP-P12048; match to protein family HMM PF01808 (510 aa)
       
    0.814
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris Hildenborough, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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