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aroA protein (Desulfovibrio vulgaris Hildenborough) - STRING interaction network
"aroA" - 3-phosphoshikimate 1-carboxyvinyltransferase in Desulfovibrio vulgaris Hildenborough
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Known Interactions
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the EPSP synthase family (439 aa)    
Predicted Functional Partners:
aroK-1
Shikimate kinase; Identified by similarity to SP-P10880; match to protein family HMM PF01202 (175 aa)
 
  0.991
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system (354 aa)
 
 
  0.986
cmk
Cytidylate kinase; Identified by similarity to SP-P23863; match to protein family HMM PF02224; match to protein family HMM TIGR00017; Belongs to the cytidylate kinase family. Type 1 subfamily (232 aa)
   
 
  0.983
aroK-2
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family (180 aa)
 
  0.981
DVU_0461
Predicted 3-dehydroquinate synthase; Identified by similarity to OMNI-NTL01AA01322 (323 aa)
 
 
 
  0.969
aroE
Shikimate dehydrogenase (NADP(+)); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) (301 aa)
   
  0.968
DVU_0462
Chorismate mutase/prephenate dehydratase; Identified by similarity to SP-P07022; match to protein family HMM PF00800; match to protein family HMM PF01817; match to protein family HMM PF01842; match to protein family HMM TIGR01807 (391 aa)
 
   
  0.962
DVU_0464
Prephenate dehydrogenase; Identified by match to protein family HMM PF02153 (255 aa)
 
     
  0.941
aroA'
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids; Belongs to the DeoC/FbaB aldolase family. ADHS subfamily (266 aa)
 
          0.897
trpG
Anthranilate synthase, glutamine amidotransferase component; Identified by similarity to SP-Q08654; match to protein family HMM PF00117; match to protein family HMM TIGR00566 (209 aa)
 
     
  0.768
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris Hildenborough, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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