STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nrfACytochrome c nitrite reductase, catalytic subunit NfrA, putative; Catalytic subunit of the cytochrome c nitrite reductase holocomplex NrfHA. Has both nitrite and sulfite reductase activities. Catalyzes the reduction of nitrite to ammonia, consuming six electrons acquired by the electron donor subunit NrfH from the menaquinone pool, in an anaerobic respiratory process of nitrite. The other biological function of the NrfHA holocomplex is to detoxify nitrite. This function is essential for the survival of this organism as it enables it to overcome inhibition by nitrite, which is produced [...] (524 aa)    
Predicted Functional Partners:
DVU_0624
NapC/NirT cytochrome c family protein; Electron donor subunit of the cytochrome c nitrite reductase holocomplex NrfHA. Acquires electrons from the menaquinone pool and mediates their transfer to the catalytic subunit NrfA in an anaerobic respiratory process of nitrite. The other biological function of the NrfHA holocomplex is to detoxify nitrite. This function is essential for the survival of this organism as it enables it to overcome inhibition by nitrite, which is produced by other organisms living in the same environment (Probable). Belongs to the NapC/NirT/NrfH family.
 
 0.999
hcp-2
Hybrid cluster protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
  
 
 0.922
hcp
Hybrid cluster protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O; Belongs to the HCP family.
    
 0.914
glnA
Glutamine synthetase, type I; Identified by similarity to SP:P12425; match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653.
   
 
 0.912
DVU_1290
Nitrate reductase, gamma subunit, putative; Identified by match to protein family HMM PF02665.
   
 
 0.906
DVU_0964
Identified by match to protein family HMM PF00208.
   
 
  0.900
amiE
Aliphatic amidase; Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide; Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.
     
  0.900
glnN
Glutamine synthetase, type III; Identified by similarity to GP:9651982; match to protein family HMM PF00120; Belongs to the glutamine synthetase family.
   
 
  0.900
DVU_1435
Membrane protein, putative; Identified by similarity to OMNI:NTL03PA01784.
     
  0.900
ccmF
Cytochrome c-type biogenesis protein CcmF; Identified by match to protein family HMM PF01578.
  
  
 0.769
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.