node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DVU_0647 | DVU_0649 | DVU_0647 | DVU_0649 | Iron compound ABC transporter, periplasmic iron compount-binding protein, putative; Identified by similarity to OMNI:DRB0007; match to protein family HMM PF01497. | Iron compound ABC transporter, permease protein; Identified by similarity to PIR:S54438; match to protein family HMM PF01032; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.999 |
DVU_0647 | cbiKp | DVU_0647 | DVU_0650 | Iron compound ABC transporter, periplasmic iron compount-binding protein, putative; Identified by similarity to OMNI:DRB0007; match to protein family HMM PF01497. | Chelatase, putative; Catalyzes the insertion of Co(2+) into sirohydrochlorin. To a lesser extent, is also able to insert Fe(2+) into sirohydrochlorin, yielding siroheme. Its periplasmic location means that it cannot participate in cobalamin biosynthesis and its genomic environment suggests it is likely to be associated with a heme or metal transport system. | 0.792 |
DVU_0647 | cobI | DVU_0647 | DVU_0646 | Iron compound ABC transporter, periplasmic iron compount-binding protein, putative; Identified by similarity to OMNI:DRB0007; match to protein family HMM PF01497. | Precorrin-2 C20-methyltransferase; Identified by similarity to SP:Q05593; match to protein family HMM PF00590; match to protein family HMM TIGR01467; Belongs to the precorrin methyltransferase family. | 0.825 |
DVU_0649 | DVU_0647 | DVU_0649 | DVU_0647 | Iron compound ABC transporter, permease protein; Identified by similarity to PIR:S54438; match to protein family HMM PF01032; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | Iron compound ABC transporter, periplasmic iron compount-binding protein, putative; Identified by similarity to OMNI:DRB0007; match to protein family HMM PF01497. | 0.999 |
DVU_0649 | cbiKp | DVU_0649 | DVU_0650 | Iron compound ABC transporter, permease protein; Identified by similarity to PIR:S54438; match to protein family HMM PF01032; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | Chelatase, putative; Catalyzes the insertion of Co(2+) into sirohydrochlorin. To a lesser extent, is also able to insert Fe(2+) into sirohydrochlorin, yielding siroheme. Its periplasmic location means that it cannot participate in cobalamin biosynthesis and its genomic environment suggests it is likely to be associated with a heme or metal transport system. | 0.793 |
DVU_0649 | cobI | DVU_0649 | DVU_0646 | Iron compound ABC transporter, permease protein; Identified by similarity to PIR:S54438; match to protein family HMM PF01032; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | Precorrin-2 C20-methyltransferase; Identified by similarity to SP:Q05593; match to protein family HMM PF00590; match to protein family HMM TIGR01467; Belongs to the precorrin methyltransferase family. | 0.808 |
DVU_1463 | cbiD | DVU_1463 | DVU_2750 | Siroheme synthase, N-terminal domain protein; Identified by match to protein family HMM TIGR01470. | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.466 |
DVU_1463 | cbiG | DVU_1463 | DVU_3169 | Siroheme synthase, N-terminal domain protein; Identified by match to protein family HMM TIGR01470. | Cobalamin biosynthesis protein CbiG; Identified by similarity to SP:Q05631; match to protein family HMM PF01890. | 0.534 |
DVU_1463 | cbiKc | DVU_1463 | DVU_1365 | Siroheme synthase, N-terminal domain protein; Identified by match to protein family HMM TIGR01470. | Heme-binding protein, putative; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. To a lesser extent, is also able to insert Fe(2+) into sirohydrochlorin, yielding siroheme. | 0.914 |
DVU_1463 | cbiKp | DVU_1463 | DVU_0650 | Siroheme synthase, N-terminal domain protein; Identified by match to protein family HMM TIGR01470. | Chelatase, putative; Catalyzes the insertion of Co(2+) into sirohydrochlorin. To a lesser extent, is also able to insert Fe(2+) into sirohydrochlorin, yielding siroheme. Its periplasmic location means that it cannot participate in cobalamin biosynthesis and its genomic environment suggests it is likely to be associated with a heme or metal transport system. | 0.914 |
DVU_1463 | cobI | DVU_1463 | DVU_0646 | Siroheme synthase, N-terminal domain protein; Identified by match to protein family HMM TIGR01470. | Precorrin-2 C20-methyltransferase; Identified by similarity to SP:Q05593; match to protein family HMM PF00590; match to protein family HMM TIGR01467; Belongs to the precorrin methyltransferase family. | 0.943 |
DVU_1463 | cobM | DVU_1463 | DVU_2748 | Siroheme synthase, N-terminal domain protein; Identified by match to protein family HMM TIGR01470. | Precorrin-4 C11-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01465. | 0.650 |
cbiD | DVU_1463 | DVU_2750 | DVU_1463 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Siroheme synthase, N-terminal domain protein; Identified by match to protein family HMM TIGR01470. | 0.466 |
cbiD | cbiG | DVU_2750 | DVU_3169 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Cobalamin biosynthesis protein CbiG; Identified by similarity to SP:Q05631; match to protein family HMM PF01890. | 0.999 |
cbiD | cbiKc | DVU_2750 | DVU_1365 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Heme-binding protein, putative; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. To a lesser extent, is also able to insert Fe(2+) into sirohydrochlorin, yielding siroheme. | 0.852 |
cbiD | cbiKp | DVU_2750 | DVU_0650 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Chelatase, putative; Catalyzes the insertion of Co(2+) into sirohydrochlorin. To a lesser extent, is also able to insert Fe(2+) into sirohydrochlorin, yielding siroheme. Its periplasmic location means that it cannot participate in cobalamin biosynthesis and its genomic environment suggests it is likely to be associated with a heme or metal transport system. | 0.857 |
cbiD | cobH | DVU_2750 | DVU_3087 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | precorrin-8X methylmutase; Identified by similarity to GP:15826199; match to protein family HMM PF02570. | 0.995 |
cbiD | cobI | DVU_2750 | DVU_0646 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Precorrin-2 C20-methyltransferase; Identified by similarity to SP:Q05593; match to protein family HMM PF00590; match to protein family HMM TIGR01467; Belongs to the precorrin methyltransferase family. | 0.972 |
cbiD | cobJ | DVU_2750 | DVU_3170 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Precorrin-3b C17-methyltransferase; Identified by similarity to SP:P21640; match to protein family HMM PF00590; match to protein family HMM TIGR01466. | 0.944 |
cbiD | cobM | DVU_2750 | DVU_2748 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Precorrin-4 C11-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01465. | 0.957 |