Co-purification, co-crystallization, Yeast2Hybrid, Genetic Interactions, etc ... as imported from primary sources.
Genes that are sometimes fused into single open reading frames.
Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Proteins whose genes are observed to be correlated in expression, across a large number of experiments.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Peptidase, U32 family; Identified by match to protein family HMM PF01136 (408 aa)
Predicted Functional Partners:
PHP domain protein; Identified by match to protein family HMM PF02231 (288 aa)
Sigma-54 dependent transcriptional regulator, putative/response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM TIGR01199 (561 aa)
Hemolysin-type calcium-binding repeat protein; Identified by match to protein family HMM PF00092; match to protein family HMM PF00353; match to protein family HMM TIGR01612 (3038 aa)
UPF0434 protein DVU_0656; Identified by similarity to OMNI-NTL02SC2888; match to protein family HMM PF03966; Belongs to the UPF0434 family (69 aa)
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882 Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris Hildenborough, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough